3DOY
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3i
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0006633 | biological_process | fatty acid biosynthetic process |
A | 0009245 | biological_process | lipid A biosynthetic process |
A | 0016020 | cellular_component | membrane |
A | 0016829 | molecular_function | lyase activity |
A | 0016836 | molecular_function | hydro-lyase activity |
A | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006633 | biological_process | fatty acid biosynthetic process |
B | 0009245 | biological_process | lipid A biosynthetic process |
B | 0016020 | cellular_component | membrane |
B | 0016829 | molecular_function | lyase activity |
B | 0016836 | molecular_function | hydro-lyase activity |
B | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0006633 | biological_process | fatty acid biosynthetic process |
C | 0009245 | biological_process | lipid A biosynthetic process |
C | 0016020 | cellular_component | membrane |
C | 0016829 | molecular_function | lyase activity |
C | 0016836 | molecular_function | hydro-lyase activity |
C | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0006633 | biological_process | fatty acid biosynthetic process |
D | 0009245 | biological_process | lipid A biosynthetic process |
D | 0016020 | cellular_component | membrane |
D | 0016829 | molecular_function | lyase activity |
D | 0016836 | molecular_function | hydro-lyase activity |
D | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
E | 0005737 | cellular_component | cytoplasm |
E | 0006633 | biological_process | fatty acid biosynthetic process |
E | 0009245 | biological_process | lipid A biosynthetic process |
E | 0016020 | cellular_component | membrane |
E | 0016829 | molecular_function | lyase activity |
E | 0016836 | molecular_function | hydro-lyase activity |
E | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
F | 0005737 | cellular_component | cytoplasm |
F | 0006633 | biological_process | fatty acid biosynthetic process |
F | 0009245 | biological_process | lipid A biosynthetic process |
F | 0016020 | cellular_component | membrane |
F | 0016829 | molecular_function | lyase activity |
F | 0016836 | molecular_function | hydro-lyase activity |
F | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL A 1001 |
Chain | Residue |
A | HIS58 |
A | GLY67 |
B | HOH3006 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL B 1002 |
Chain | Residue |
A | HOH3025 |
B | HIS58 |
B | GLY67 |
B | HOH3026 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL C 1003 |
Chain | Residue |
C | GLY67 |
D | HOH3210 |
site_id | AC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE CL D 1004 |
Chain | Residue |
D | GLY67 |
site_id | AC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL E 1005 |
Chain | Residue |
E | GLY67 |
F | HOH3239 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CL F 1006 |
Chain | Residue |
E | HOH3133 |
E | HOH3262 |
F | GLY67 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE BEN A 2001 |
Chain | Residue |
A | GLN40 |
A | GLU124 |
A | VAL125 |
E | THR138 |
E | VAL145 |
E | GLU148 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE BEN A 2005 |
Chain | Residue |
A | MET131 |
A | MET154 |
F | TRP87 |
F | ASP90 |
F | ILE93 |
site_id | AC9 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE 2BE A 3001 |
Chain | Residue |
A | PHE59 |
A | LYS62 |
A | PHE109 |
A | ARG110 |
A | ILE111 |
A | PRO112 |
B | ILE98 |
B | TYR100 |
B | ARG158 |
B | HOH3370 |
site_id | BC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE BEN B 2007 |
Chain | Residue |
B | TRP87 |
B | GLY88 |
E | LEU86 |
E | TRP87 |
E | GLY130 |
E | HOH3395 |
site_id | BC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE BEN B 2009 |
Chain | Residue |
B | ILE20 |
B | LEU21 |
B | PRO22 |
B | HIS23 |
B | PHE83 |
B | ALA94 |
B | LYS97 |
B | ILE98 |
B | VAL99 |
B | HOH3479 |
site_id | BC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE BEN C 2004 |
Chain | Residue |
C | ALA38 |
C | THR84 |
C | SER85 |
C | LEU86 |
C | TRP87 |
C | GLY88 |
D | GLN40 |
site_id | BC4 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE 2BE C 3002 |
Chain | Residue |
C | LEU21 |
C | PRO22 |
C | HIS23 |
C | GLY79 |
C | ILE98 |
C | VAL99 |
C | PHE101 |
C | ARG158 |
D | PHE59 |
D | ILE64 |
site_id | BC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE BEN E 2008 |
Chain | Residue |
A | THR138 |
A | GLU148 |
E | GLU124 |
E | VAL125 |
E | LEU126 |
E | HOH3197 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1mka |
Chain | Residue | Details |
A | GLU72 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1mka |
Chain | Residue | Details |
B | GLU72 |
site_id | CSA3 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1mka |
Chain | Residue | Details |
C | GLU72 |
site_id | CSA4 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1mka |
Chain | Residue | Details |
D | GLU72 |
site_id | CSA5 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1mka |
Chain | Residue | Details |
E | GLU72 |
site_id | CSA6 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1mka |
Chain | Residue | Details |
F | GLU72 |