3DON

Crystal structure of shikimate dehydrogenase from Staphylococcus epidermidis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0019632	biological_process	shikimate metabolic process
A	0050661	molecular_function	NADP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 278

Chain	Residue
A	GLN77
A	VAL81
A	GLY131
A	ASN134
A	GLU135
A	LYS138
A	HOH312
A	HOH465

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00222

Chain	Residue	Details
A	LYS64

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00222, ECO:0000269|PubMed:19215302

Chain	Residue	Details
A	SER13
A	THR60
A	ASN85
A	ASP100
A	GLN239

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00222

Chain	Residue	Details
A	GLU76
A	GLY124
A	ASN148
A	ILE209
A	TYR211
A	GLY232

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site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Plays a major role in the catalytic process and a minor role in the substrate binding => ECO:0000269|PubMed:19215302

Chain	Residue	Details
A	TYR211

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1nvt

Chain	Residue	Details
A	ASP91

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