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3DOF

Complex of ARL2 and BART, Crystal Form 2

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005730cellular_componentnucleolus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005758cellular_componentmitochondrial intermembrane space
A0005759cellular_componentmitochondrial matrix
A0005794cellular_componentGolgi apparatus
A0005813cellular_componentcentrosome
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005925cellular_componentfocal adhesion
A0005929cellular_componentcilium
A0006110biological_processregulation of glycolytic process
A0006457biological_processprotein folding
A0007098biological_processcentrosome cycle
A0010811biological_processpositive regulation of cell-substrate adhesion
A0015630cellular_componentmicrotubule cytoskeleton
A0016328cellular_componentlateral plasma membrane
A0019003molecular_functionGDP binding
A0031113biological_processregulation of microtubule polymerization
A0031116biological_processpositive regulation of microtubule polymerization
A0034260biological_processnegative regulation of GTPase activity
A0051457biological_processmaintenance of protein location in nucleus
A0070830biological_processbicellular tight junction assembly
A1903715biological_processregulation of aerobic respiration
B0003713molecular_functiontranscription coactivator activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005758cellular_componentmitochondrial intermembrane space
B0005759cellular_componentmitochondrial matrix
B0005813cellular_componentcentrosome
B0005819cellular_componentspindle
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005929cellular_componentcilium
B0007165biological_processsignal transduction
B0030496cellular_componentmidbody
B0030695molecular_functionGTPase regulator activity
B0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
B0045893biological_processpositive regulation of DNA-templated transcription
B0051457biological_processmaintenance of protein location in nucleus
Functional Information from PDB Data
site_idAC1
Number of Residues19
DetailsBINDING SITE FOR RESIDUE GTP A 201
ChainResidue
ALEU24
ATHR47
AGLY69
AASN125
ALYS126
AASP128
ALEU129
ASER158
AALA159
AVAL160
AMG193
AASP25
AASN26
AALA27
AGLY28
ALYS29
ATHR30
ATHR31
AILE44

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 193
ChainResidue
ATHR30
ATHR47
AGTP201

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AGLY23
AASP66
AGLY68
AASN125

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9D0J4
ChainResidueDetails
ASER45

site_idSWS_FT_FI3
Number of Residues1
DetailsLIPID: N-myristoyl glycine => ECO:0000255
ChainResidueDetails
AGLY2

site_idSWS_FT_FI4
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
ChainResidueDetails
ALYS71

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1ksj
ChainResidueDetails
AGLN70

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PDB entries from 2024-05-01

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