3DMO
1.6 A crystal structure of cytidine deaminase from Burkholderia pseudomallei
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004126 | molecular_function | cytidine deaminase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| A | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004126 | molecular_function | cytidine deaminase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| B | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004126 | molecular_function | cytidine deaminase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| C | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004126 | molecular_function | cytidine deaminase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| D | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN D 131 |
| Chain | Residue |
| D | CYS53 |
| D | CYS88 |
| D | CYS91 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN C 131 |
| Chain | Residue |
| C | CYS53 |
| C | CYS88 |
| C | CYS91 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 131 |
| Chain | Residue |
| B | CYS53 |
| B | CYS88 |
| B | CYS91 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 131 |
| Chain | Residue |
| A | CYS53 |
| A | CYS88 |
| A | CYS91 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PO4 B 132 |
| Chain | Residue |
| B | THR2 |
| B | HIS3 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MRD D 132 |
| Chain | Residue |
| A | LEU129 |
| B | ALA46 |
| B | SER47 |
| B | TYR48 |
| D | PHE24 |
| D | ASN42 |
| D | GLU44 |
| D | CYS51 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MRD A 132 |
| Chain | Residue |
| A | ASN42 |
| A | GLU44 |
| C | ALA46 |
| C | SER47 |
| C | TYR48 |
| D | LEU129 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MRD C 132 |
| Chain | Residue |
| A | ALA46 |
| A | SER47 |
| A | TYR48 |
| C | ASN42 |
| C | GLU44 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MRD B 133 |
| Chain | Residue |
| B | ASN42 |
| B | GLU44 |
| D | ALA46 |
| D | SER47 |
| D | TYR48 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 43 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. CAErtALfsalaagyrpgefaaiavvgethgpia......PCga......CrqvM |
| Chain | Residue | Details |
| A | CYS53-MET95 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ctt |
| Chain | Residue | Details |
| A | GLU55 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ctt |
| Chain | Residue | Details |
| B | GLU55 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ctt |
| Chain | Residue | Details |
| C | GLU55 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ctt |
| Chain | Residue | Details |
| D | GLU55 |
