3DMD
Structures and Conformations in Solution of the Signal Recognition Particle Receptor from the archaeon Pyrococcus furiosus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005047 | molecular_function | signal recognition particle binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006605 | biological_process | protein targeting |
| A | 0006612 | biological_process | protein targeting to membrane |
| A | 0006614 | biological_process | SRP-dependent cotranslational protein targeting to membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005047 | molecular_function | signal recognition particle binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006605 | biological_process | protein targeting |
| B | 0006612 | biological_process | protein targeting to membrane |
| B | 0006614 | biological_process | SRP-dependent cotranslational protein targeting to membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005047 | molecular_function | signal recognition particle binding |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006605 | biological_process | protein targeting |
| C | 0006612 | biological_process | protein targeting to membrane |
| C | 0006614 | biological_process | SRP-dependent cotranslational protein targeting to membrane |
| C | 0016020 | cellular_component | membrane |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 323 |
| Chain | Residue |
| A | ASN132 |
| A | GLY133 |
| A | SER134 |
| A | GLY135 |
| A | LYS136 |
| A | THR137 |
| A | ARG163 |
| A | HOH357 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 323 |
| Chain | Residue |
| B | GLY133 |
| B | SER134 |
| B | GLY135 |
| B | LYS136 |
| B | THR137 |
| B | ARG163 |
| B | HOH343 |
| B | HOH445 |
| B | HOH499 |
| B | ASN132 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 324 |
| Chain | Residue |
| A | ALA63 |
| A | LEU64 |
| A | ARG256 |
| A | HOH336 |
| A | HOH348 |
| A | HOH408 |
| A | HOH446 |
| A | HOH454 |
| C | LYS229 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 324 |
| Chain | Residue |
| A | ARG221 |
| A | LYS229 |
| B | ALA63 |
| B | LEU64 |
| B | ARG256 |
| B | HOH347 |
| B | HOH360 |
| B | HOH419 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 C 323 |
| Chain | Residue |
| C | ASN132 |
| C | GLY133 |
| C | SER134 |
| C | GLY135 |
| C | LYS136 |
| C | THR137 |
| C | ARG163 |
| C | HOH344 |
| C | HOH436 |
| C | HOH459 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 325 |
| Chain | Residue |
| A | ARG84 |
| C | ARG35 |
| C | ILE36 |
| C | LEU37 |
| C | THR38 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 324 |
| Chain | Residue |
| A | LYS81 |
| A | HOH414 |
| B | ASN259 |
| B | LYS263 |
| B | HOH364 |
| C | ASP34 |
| C | ARG35 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 325 |
| Chain | Residue |
| A | TYR186 |
| A | HOH424 |
| B | ARG163 |
| B | ARG216 |
| B | HOH335 |
| B | HOH469 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 325 |
| Chain | Residue |
| C | ASN132 |
| C | ARG216 |
| C | HOH460 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 326 |
| Chain | Residue |
| A | ASN132 |
| A | ARG216 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 327 |
| Chain | Residue |
| A | PHE162 |
| A | ARG163 |
| A | ALA164 |
| A | GLY165 |
| A | ALA166 |
| A | ARG216 |
| A | HOH474 |
| B | TYR186 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 326 |
| Chain | Residue |
| C | PHE162 |
| C | ARG163 |
| C | GLY165 |
| C | ALA166 |
| C | TYR186 |
| C | ARG216 |
| C | HOH460 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 326 |
| Chain | Residue |
| B | ASN132 |
| B | ARG163 |
| B | ARG216 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 327 |
| Chain | Residue |
| C | TRP146 |
| C | HIS150 |
| C | PRO306 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 328 |
| Chain | Residue |
| B | ARG221 |
| B | LYS229 |
| C | ALA63 |
| C | LEU64 |
| C | ARG256 |
| C | HOH368 |
| C | HOH413 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 329 |
| Chain | Residue |
| C | SER185 |
| C | ALA188 |
| A | GLU59 |
| A | HOH461 |
| C | HIS184 |
Functional Information from PROSITE/UniProt
| site_id | PS00300 |
| Number of Residues | 14 |
| Details | SRP54 SRP54-type proteins GTP-binding domain signature. PIlFVGVGQgYddL |
| Chain | Residue | Details |
| B | PRO291-LEU304 |
