Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3DL8

Structure of the complex of aquifex aeolicus SecYEG and bacillus subtilis SecA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006605	biological_process	protein targeting
A	0006886	biological_process	intracellular protein transport
A	0008564	molecular_function	protein-exporting ATPase activity
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0017038	biological_process	protein import
A	0031522	cellular_component	cell envelope Sec protein transport complex
A	0043952	biological_process	protein transport by the Sec complex
A	0045121	cellular_component	membrane raft
A	0046872	molecular_function	metal ion binding
A	0065002	biological_process	intracellular protein transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0006605	biological_process	protein targeting
B	0006886	biological_process	intracellular protein transport
B	0008564	molecular_function	protein-exporting ATPase activity
B	0015031	biological_process	protein transport
B	0016020	cellular_component	membrane
B	0017038	biological_process	protein import
B	0031522	cellular_component	cell envelope Sec protein transport complex
B	0043952	biological_process	protein transport by the Sec complex
B	0045121	cellular_component	membrane raft
B	0046872	molecular_function	metal ion binding
B	0065002	biological_process	intracellular protein transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0006605	biological_process	protein targeting
C	0006886	biological_process	intracellular protein transport
C	0008320	molecular_function	protein transmembrane transporter activity
C	0009306	biological_process	protein secretion
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0043952	biological_process	protein transport by the Sec complex
C	0065002	biological_process	intracellular protein transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006605	biological_process	protein targeting
D	0006886	biological_process	intracellular protein transport
D	0008320	molecular_function	protein transmembrane transporter activity
D	0009306	biological_process	protein secretion
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0043952	biological_process	protein transport by the Sec complex
D	0065002	biological_process	intracellular protein transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0009306	biological_process	protein secretion
E	0015031	biological_process	protein transport
E	0015450	molecular_function	protein-transporting ATPase activity
E	0016020	cellular_component	membrane
E	0043952	biological_process	protein transport by the Sec complex
E	0065002	biological_process	intracellular protein transmembrane transport
F	0005886	cellular_component	plasma membrane
F	0009306	biological_process	protein secretion
F	0015031	biological_process	protein transport
F	0015450	molecular_function	protein-transporting ATPase activity
F	0016020	cellular_component	membrane
F	0043952	biological_process	protein transport by the Sec complex
F	0065002	biological_process	intracellular protein transmembrane transport
G	0005048	molecular_function	signal sequence binding
G	0005886	cellular_component	plasma membrane
G	0006605	biological_process	protein targeting
G	0006616	biological_process	SRP-dependent cotranslational protein targeting to membrane, translocation
G	0008320	molecular_function	protein transmembrane transporter activity
G	0015031	biological_process	protein transport
G	0016020	cellular_component	membrane
G	0031522	cellular_component	cell envelope Sec protein transport complex
G	0043952	biological_process	protein transport by the Sec complex
G	0065002	biological_process	intracellular protein transmembrane transport
H	0005048	molecular_function	signal sequence binding
H	0005886	cellular_component	plasma membrane
H	0006605	biological_process	protein targeting
H	0006616	biological_process	SRP-dependent cotranslational protein targeting to membrane, translocation
H	0008320	molecular_function	protein transmembrane transporter activity
H	0015031	biological_process	protein transport
H	0016020	cellular_component	membrane
H	0031522	cellular_component	cell envelope Sec protein transport complex
H	0043952	biological_process	protein transport by the Sec complex
H	0065002	biological_process	intracellular protein transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00755
Number of Residues	20
Details	SECY_1 Protein secY signature 1. TVFaLGVmPYIsASIMMQLL

Chain	Residue	Details
G	THR71-LEU90

site_id	PS00756
Number of Residues	18
Details	SECY_2 Protein secY signature 2. WIaDrITek.GIGNGaSLI

Chain	Residue	Details
G	TRP171-ILE188

site_id	PS01312
Number of Residues	16
Details	SECA SecA family signature. VtIATNMAGRGtDIkL

Chain	Residue	Details
A	VAL480-LEU495

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15256599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19850053","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TF2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3JV2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01382","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12242434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15256599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16989859","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19850053","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1M74","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1TF2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3JV2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01382","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12242434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15256599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16989859","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1M74","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1TF2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	100
Details	Transmembrane: {"description":"Helical; Name=1"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	66
Details	Transmembrane: {"description":"Discontinuously helical; Name=Helix 2"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	14
Details	Intramembrane: {"description":"Helical; Name=Helix 2A"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	8
Details	Intramembrane: {}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	40
Details	Intramembrane: {"description":"Helical; Name=Helix 2B"}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	180
Details	Topological domain: {"description":"Cytoplasmic"}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=3"}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	122
Details	Topological domain: {"description":"Periplasmic"}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=4"}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	36
Details	Transmembrane: {"description":"Helical; Name=5"}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=6"}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	36
Details	Transmembrane: {"description":"Helical; Name=7"}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	42
Details	Transmembrane: {"description":"Helical; Name=8"}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	48
Details	Transmembrane: {"description":"Helical; Name=9"}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=10"}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	62
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	42
Details	Transmembrane: {"description":"Helical; Name=2"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)