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3DKI

2.1 A X-ray structure of CysM (Rv1336) from Mycobacterium tuberculosis an O-phosphoserine dependent cysteine synthase

Functional Information from GO Data
ChainGOidnamespacecontents
A0004124molecular_functioncysteine synthase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006535biological_processcysteine biosynthetic process from serine
A0008652biological_processamino acid biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0019344biological_processcysteine biosynthetic process
A0030170molecular_functionpyridoxal phosphate binding
A0032991cellular_componentprotein-containing complex
A0033847molecular_functionO-phosphoserine sulfhydrylase activity
A0080146molecular_functionL-cysteine desulfhydrase activity
B0004124molecular_functioncysteine synthase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006535biological_processcysteine biosynthetic process from serine
B0008652biological_processamino acid biosynthetic process
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0019344biological_processcysteine biosynthetic process
B0030170molecular_functionpyridoxal phosphate binding
B0032991cellular_componentprotein-containing complex
B0033847molecular_functionO-phosphoserine sulfhydrylase activity
B0080146molecular_functionL-cysteine desulfhydrase activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE NA B 324
ChainResidue
BALA140
BASN143
BTRP146
BHOH376

Functional Information from PROSITE/UniProt
site_idPS00901
Number of Residues19
DetailsCYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEdrn.PTgSIKdRpAvrM
ChainResidueDetails
ALYS40-MET58

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:18771296, ECO:0000269|PubMed:18799456, ECO:0000269|PubMed:19101553
ChainResidueDetails
AASN81
ASER265
BASN81
BSER265

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AGLY184
BGLY184

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000305
ChainResidueDetails
AARG220
BARG220

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: N6-(pyridoxal phosphate)lysine
ChainResidueDetails
ALLP51
BLLP51

218853

PDB entries from 2024-04-24

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