3DHI
Crystal Structure of Reduced Toluene 4-Monoxygenase Hydroxylase Complexed with Effector Protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0009056 | biological_process | catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| A | 0042203 | biological_process | toluene catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0009056 | biological_process | catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| B | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| B | 0042203 | biological_process | toluene catabolic process |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0009056 | biological_process | catabolic process |
| C | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| C | 0042203 | biological_process | toluene catabolic process |
| E | 0004497 | molecular_function | monooxygenase activity |
| E | 0009056 | biological_process | catabolic process |
| E | 0042203 | biological_process | toluene catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE A 600 |
| Chain | Residue |
| A | GLU104 |
| A | GLU134 |
| A | HIS137 |
| A | GLU231 |
| A | HOH501 |
| A | FE601 |
| A | ACT602 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE A 601 |
| Chain | Residue |
| A | GLU231 |
| A | HIS234 |
| A | FE600 |
| A | ACT602 |
| A | GLU134 |
| A | GLU197 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT A 602 |
| Chain | Residue |
| A | GLU104 |
| A | GLU134 |
| A | LEU192 |
| A | PHE196 |
| A | GLU197 |
| A | GLU231 |
| A | HOH501 |
| A | FE600 |
| A | FE601 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1PE A 603 |
| Chain | Residue |
| A | TRP167 |
| A | GLY334 |
| A | TRP338 |
| A | THR341 |
| A | THR392 |
| A | LEU393 |
| A | PRO394 |
| A | PRO403 |
| A | LEU464 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1PE B 604 |
| Chain | Residue |
| B | GLN100 |
| B | ARG104 |
| B | GLN236 |
| B | GLN237 |
| B | TRP240 |
| B | PRO248 |
| B | ASP252 |
| B | HOH792 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BTB C 605 |
| Chain | Residue |
| A | HOH732 |
| C | VAL20 |
| C | LYS33 |
| C | TYR36 |
| C | HIS37 |
| C | HOH328 |
| E | ASP93 |
| E | HOH591 |
| E | HOH676 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19033467, ECO:0000269|PubMed:19290655, ECO:0000269|PubMed:19705873, ECO:0000269|PubMed:22264099, ECO:0000269|PubMed:25248368, ECO:0000269|PubMed:28346937, ECO:0007744|PDB:3Q14, ECO:0007744|PDB:3Q2A, ECO:0007744|PDB:3Q3M, ECO:0007744|PDB:3Q3N, ECO:0007744|PDB:3Q3O, ECO:0007744|PDB:3RI7, ECO:0007744|PDB:3RMK, ECO:0007744|PDB:4P1B, ECO:0007744|PDB:4P1C, ECO:0007744|PDB:5TDS, ECO:0007744|PDB:5TDT, ECO:0007744|PDB:5TDU, ECO:0007744|PDB:5TDV |
| Chain | Residue | Details |
| A | GLU104 | |
| A | GLU134 | |
| A | HIS137 | |
| A | GLU197 | |
| A | GLU231 | |
| A | HIS234 |
