3DHH

Crystal Structure of Resting State Toluene 4-Monoxygenase Hydroxylase Complexed with Effector Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0018638	molecular_function	toluene 4-monooxygenase activity
A	0042203	biological_process	toluene catabolic process
A	0046872	molecular_function	metal ion binding
B	0004497	molecular_function	monooxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
B	0018638	molecular_function	toluene 4-monooxygenase activity
B	0042203	biological_process	toluene catabolic process
C	0004497	molecular_function	monooxygenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0018638	molecular_function	toluene 4-monooxygenase activity
C	0042203	biological_process	toluene catabolic process
E	0004497	molecular_function	monooxygenase activity
E	0042203	biological_process	toluene catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 501

Chain	Residue
A	GLU104
A	GLU134
A	HIS137
A	FE502
A	1PE505
A	HOH512
A	HOH515

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 502

Chain	Residue
A	GLU231
A	HIS234
A	FE501
A	1PE505
A	HOH512
A	GLU134
A	GLU197

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE BML A 503

Chain	Residue
A	TRP167
A	GLY334
A	VAL335
A	TRP338
A	THR341
A	PRO403
A	VAL405
A	BML507

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BML A 504

Chain	Residue
A	TRP338
A	GLU391
A	THR392
A	LEU393
A	THR463
A	LEU464

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE 1PE A 505

Chain	Residue
A	ALA99
A	ILE100
A	GLY103
A	GLU104
A	GLU134
A	TYR162
A	PHE176
A	GLU197
A	FE501
A	FE502
A	HOH512

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE BML A 507

Chain	Residue
A	TRP167
A	LEU393
A	PRO394
A	VAL396
A	GLN401
A	ILE402
A	PRO403
A	ILE450
A	BML503

---

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BTB A 509

Chain	Residue
A	GLU214
A	SER287
A	HOH837
A	HOH860
E	ASP44
E	ARG45
E	ARG46

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE BML B 508

Chain	Residue
A	MET3
A	PRO56
B	GLU91
B	GLN95
B	PHE98
B	THR164
B	HIS165
B	TYR168
B	HOH346

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE BML E 507

Chain	Residue
A	ARG6
A	TYR51
E	MET74
E	GLN75
E	ALA90
E	ILE95

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19033467","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19290655","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19705873","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22264099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25248368","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28346937","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RI7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RMK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P1B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P1C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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