3DH2
Crystal structure of ribonuclease Sa2 with guanosine-3'-cyclophosphate prepared by cocrystallization
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004521 | molecular_function | RNA endonuclease activity |
| C | 0004540 | molecular_function | RNA nuclease activity |
| D | 0003723 | molecular_function | RNA binding |
| D | 0004521 | molecular_function | RNA endonuclease activity |
| D | 0004540 | molecular_function | RNA nuclease activity |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c54 |
| Chain | Residue | Details |
| A | GLU56 | |
| A | HIS86 | |
| A | ARG67 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c54 |
| Chain | Residue | Details |
| B | GLU56 | |
| B | HIS86 | |
| B | ARG67 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c54 |
| Chain | Residue | Details |
| C | GLU56 | |
| C | HIS86 | |
| C | ARG67 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1c54 |
| Chain | Residue | Details |
| D | GLU56 | |
| D | HIS86 | |
| D | ARG67 |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 459 |
| Chain | Residue | Details |
| A | GLU56 | proton shuttle (general acid/base) |
| A | ARG67 | activator, transition state stabiliser |
| A | ARG71 | activator, transition state stabiliser |
| A | HIS86 | proton shuttle (general acid/base) |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 459 |
| Chain | Residue | Details |
| B | GLU56 | proton shuttle (general acid/base) |
| B | ARG67 | activator, transition state stabiliser |
| B | ARG71 | activator, transition state stabiliser |
| B | HIS86 | proton shuttle (general acid/base) |
| site_id | MCSA3 |
| Number of Residues | 4 |
| Details | M-CSA 459 |
| Chain | Residue | Details |
| C | GLU56 | proton shuttle (general acid/base) |
| C | ARG67 | activator, transition state stabiliser |
| C | ARG71 | activator, transition state stabiliser |
| C | HIS86 | proton shuttle (general acid/base) |
| site_id | MCSA4 |
| Number of Residues | 4 |
| Details | M-CSA 459 |
| Chain | Residue | Details |
| D | GLU56 | proton shuttle (general acid/base) |
| D | ARG67 | activator, transition state stabiliser |
| D | ARG71 | activator, transition state stabiliser |
| D | HIS86 | proton shuttle (general acid/base) |
