3DGE
Structure of a histidine kinase-response regulator complex reveals insights into Two-component signaling and a novel cis-autophosphorylation mechanism
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| C | 0000156 | molecular_function | phosphorelay response regulator activity |
| C | 0000160 | biological_process | phosphorelay signal transduction system |
| C | 0003677 | molecular_function | DNA binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000156 | molecular_function | phosphorelay response regulator activity |
| D | 0000160 | biological_process | phosphorelay signal transduction system |
| D | 0003677 | molecular_function | DNA binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 150 |
| Chain | Residue |
| A | HIS260 |
| C | ASP53 |
| C | MET55 |
| C | THR83 |
| C | ALA84 |
| C | LYS105 |
| C | HOH177 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 160 |
| Chain | Residue |
| D | MET55 |
| D | THR83 |
| D | ALA84 |
| D | LYS105 |
| D | HOH196 |
| B | HIS260 |
| D | ASP53 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADP A 500 |
| Chain | Residue |
| A | ASN380 |
| A | TYR384 |
| A | ASP411 |
| A | TYR429 |
| A | ARG430 |
| A | GLY441 |
| A | THR442 |
| A | GLY443 |
| A | LEU444 |
| A | GLY445 |
| A | LEU446 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ADP B 600 |
| Chain | Residue |
| B | ASN376 |
| B | ASN380 |
| B | LYS383 |
| B | TYR384 |
| B | ASP411 |
| B | TYR429 |
| B | ARG430 |
| B | GLY441 |
| B | THR442 |
| B | GLY443 |
| B | LEU444 |
| B | GLY445 |
| B | LEU446 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CIT N 3 |
| Chain | Residue |
| A | ASN304 |
| A | ARG371 |
