Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3DFY

Crystal structure of apo dipeptide epimerase from Thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006518	biological_process	peptide metabolic process
A	0016853	molecular_function	isomerase activity
A	0016854	molecular_function	racemase and epimerase activity
A	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0046872	molecular_function	metal ion binding
A	0071555	biological_process	cell wall organization
A	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
B	0006518	biological_process	peptide metabolic process
B	0016853	molecular_function	isomerase activity
B	0016854	molecular_function	racemase and epimerase activity
B	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
B	0016998	biological_process	cell wall macromolecule catabolic process
B	0046872	molecular_function	metal ion binding
B	0071555	biological_process	cell wall organization
B	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
C	0006518	biological_process	peptide metabolic process
C	0016853	molecular_function	isomerase activity
C	0016854	molecular_function	racemase and epimerase activity
C	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
C	0016998	biological_process	cell wall macromolecule catabolic process
C	0046872	molecular_function	metal ion binding
C	0071555	biological_process	cell wall organization
C	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
D	0006518	biological_process	peptide metabolic process
D	0016853	molecular_function	isomerase activity
D	0016854	molecular_function	racemase and epimerase activity
D	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
D	0016998	biological_process	cell wall macromolecule catabolic process
D	0046872	molecular_function	metal ion binding
D	0071555	biological_process	cell wall organization
D	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
E	0006518	biological_process	peptide metabolic process
E	0016853	molecular_function	isomerase activity
E	0016854	molecular_function	racemase and epimerase activity
E	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
E	0016998	biological_process	cell wall macromolecule catabolic process
E	0046872	molecular_function	metal ion binding
E	0071555	biological_process	cell wall organization
E	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
F	0006518	biological_process	peptide metabolic process
F	0016853	molecular_function	isomerase activity
F	0016854	molecular_function	racemase and epimerase activity
F	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
F	0016998	biological_process	cell wall macromolecule catabolic process
F	0046872	molecular_function	metal ion binding
F	0071555	biological_process	cell wall organization
F	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
G	0006518	biological_process	peptide metabolic process
G	0016853	molecular_function	isomerase activity
G	0016854	molecular_function	racemase and epimerase activity
G	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
G	0016998	biological_process	cell wall macromolecule catabolic process
G	0046872	molecular_function	metal ion binding
G	0071555	biological_process	cell wall organization
G	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
H	0006518	biological_process	peptide metabolic process
H	0016853	molecular_function	isomerase activity
H	0016854	molecular_function	racemase and epimerase activity
H	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
H	0016998	biological_process	cell wall macromolecule catabolic process
H	0046872	molecular_function	metal ion binding
H	0071555	biological_process	cell wall organization
H	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
I	0006518	biological_process	peptide metabolic process
I	0016853	molecular_function	isomerase activity
I	0016854	molecular_function	racemase and epimerase activity
I	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
I	0016998	biological_process	cell wall macromolecule catabolic process
I	0046872	molecular_function	metal ion binding
I	0071555	biological_process	cell wall organization
I	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
J	0006518	biological_process	peptide metabolic process
J	0016853	molecular_function	isomerase activity
J	0016854	molecular_function	racemase and epimerase activity
J	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
J	0016998	biological_process	cell wall macromolecule catabolic process
J	0046872	molecular_function	metal ion binding
J	0071555	biological_process	cell wall organization
J	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
K	0006518	biological_process	peptide metabolic process
K	0016853	molecular_function	isomerase activity
K	0016854	molecular_function	racemase and epimerase activity
K	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
K	0016998	biological_process	cell wall macromolecule catabolic process
K	0046872	molecular_function	metal ion binding
K	0071555	biological_process	cell wall organization
K	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
L	0006518	biological_process	peptide metabolic process
L	0016853	molecular_function	isomerase activity
L	0016854	molecular_function	racemase and epimerase activity
L	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
L	0016998	biological_process	cell wall macromolecule catabolic process
L	0046872	molecular_function	metal ion binding
L	0071555	biological_process	cell wall organization
L	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
M	0006518	biological_process	peptide metabolic process
M	0016853	molecular_function	isomerase activity
M	0016854	molecular_function	racemase and epimerase activity
M	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
M	0016998	biological_process	cell wall macromolecule catabolic process
M	0046872	molecular_function	metal ion binding
M	0071555	biological_process	cell wall organization
M	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
N	0006518	biological_process	peptide metabolic process
N	0016853	molecular_function	isomerase activity
N	0016854	molecular_function	racemase and epimerase activity
N	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
N	0016998	biological_process	cell wall macromolecule catabolic process
N	0046872	molecular_function	metal ion binding
N	0071555	biological_process	cell wall organization
N	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
O	0006518	biological_process	peptide metabolic process
O	0016853	molecular_function	isomerase activity
O	0016854	molecular_function	racemase and epimerase activity
O	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
O	0016998	biological_process	cell wall macromolecule catabolic process
O	0046872	molecular_function	metal ion binding
O	0071555	biological_process	cell wall organization
O	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity
P	0006518	biological_process	peptide metabolic process
P	0016853	molecular_function	isomerase activity
P	0016854	molecular_function	racemase and epimerase activity
P	0016855	molecular_function	racemase and epimerase activity, acting on amino acids and derivatives
P	0016998	biological_process	cell wall macromolecule catabolic process
P	0046872	molecular_function	metal ion binding
P	0071555	biological_process	cell wall organization
P	0103031	molecular_function	L-Ala-D/L-Glu epimerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 401

Chain	Residue
A	ASP188
A	GLU216
A	ASP241

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
B	ASP188
B	GLU216
B	ASP241

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 401

Chain	Residue
C	ASP188
C	GLU216
C	ASP241

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 401

Chain	Residue
D	ASP188
D	GLU216
D	ASP241

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG E 401

Chain	Residue
E	ASP188
E	GLU216
E	ASP241

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 401

Chain	Residue
F	ASP188
F	GLU216
F	ASP241

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG G 401

Chain	Residue
G	ASP188
G	GLU216
G	ASP241

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG H 401

Chain	Residue
H	ASP188
H	GLU216
H	ASP241

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG I 401

Chain	Residue
I	ASP188
I	GLU216
I	ASP241

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG J 401

Chain	Residue
J	ASP188
J	GLU216
J	ASP241

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG K 401

Chain	Residue
K	ASP188
K	GLU216
K	ASP241

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG L 401

Chain	Residue
L	ASP188
L	GLU216
L	ASP241

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG M 401

Chain	Residue
M	ASP188
M	GLU216
M	ASP241
M	GLU242

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG N 401

Chain	Residue
N	ASP188
N	ASN190
N	GLU216
N	ASP241

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG O 401

Chain	Residue
O	ASP188
O	GLU216
O	ASP241

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG P 401

Chain	Residue
P	ASP188
P	GLU216
P	ASP241

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Active site: {"description":"Proton acceptor; specific for (R)-substrate epimerization","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	16
Details	Active site: {"description":"Proton acceptor; specific for (S)-substrate epimerization","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	144
Details	Binding site: {}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
A	ASP317
A	LYS161
A	LYS159

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
J	ASP317
J	LYS161
J	LYS159

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
K	ASP317
K	LYS161
K	LYS159

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
L	ASP317
L	LYS161
L	LYS159

site_id	CSA13
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
M	ASP317
M	LYS161
M	LYS159

site_id	CSA14
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
N	ASP317
N	LYS161
N	LYS159

site_id	CSA15
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
O	ASP317
O	LYS161
O	LYS159

site_id	CSA16
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
P	ASP317
P	LYS161
P	LYS159

site_id	CSA17
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
A	LYS161
A	LYS265

site_id	CSA18
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
B	LYS161
B	LYS265

site_id	CSA19
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
C	LYS161
C	LYS265

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
B	ASP317
B	LYS161
B	LYS159

site_id	CSA20
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
D	LYS161
D	LYS265

site_id	CSA21
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
E	LYS161
E	LYS265

site_id	CSA22
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
F	LYS161
F	LYS265

site_id	CSA23
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
G	LYS161
G	LYS265

site_id	CSA24
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
H	LYS161
H	LYS265

site_id	CSA25
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
I	LYS161
I	LYS265

site_id	CSA26
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
J	LYS161
J	LYS265

site_id	CSA27
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
K	LYS161
K	LYS265

site_id	CSA28
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
L	LYS161
L	LYS265

site_id	CSA29
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
M	LYS161
M	LYS265

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
C	ASP317
C	LYS161
C	LYS159

site_id	CSA30
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
N	LYS161
N	LYS265

site_id	CSA31
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
O	LYS161
O	LYS265

site_id	CSA32
Number of Residues	2
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
P	LYS161
P	LYS265

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
D	ASP317
D	LYS161
D	LYS159

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
E	ASP317
E	LYS161
E	LYS159

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
F	ASP317
F	LYS161
F	LYS159

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
G	ASP317
G	LYS161
G	LYS159

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
H	ASP317
H	LYS161
H	LYS159

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1muc

Chain	Residue	Details
I	ASP317
I	LYS161
I	LYS159

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)