Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 499 |
| Chain | Residue |
| A | PRO168 |
| A | GLU269 |
| A | HOH531 |
| A | HOH554 |
| A | HOH949 |
| A | HOH971 |
| A | HOH972 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 500 |
| Chain | Residue |
| A | HOH557 |
| A | HOH640 |
| A | HOH874 |
| A | HOH875 |
| A | SER135 |
| A | ACT501 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT A 501 |
| Chain | Residue |
| A | ASP132 |
| A | PHE133 |
| A | SER135 |
| A | CA500 |
| A | HOH640 |
| A | HOH648 |
| A | HOH874 |
| A | HOH875 |
| A | HOH908 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A 502 |
| Chain | Residue |
| A | ASN119 |
| A | ASN121 |
| A | THR122 |
| A | ASP128 |
| A | HOH691 |
| A | HOH960 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 503 |
| Chain | Residue |
| A | THR277 |
| A | ILE374 |
| A | TYR375 |
| A | LEU376 |
| A | HOH783 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 504 |
| Chain | Residue |
| A | SER171 |
| A | THR172 |
| A | PHE180 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 505 |
| Chain | Residue |
| A | LEU29 |
| A | ASP48 |
| A | ARG49 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 506 |
| Chain | Residue |
| A | GLU89 |
| A | ASN386 |
| A | ILE387 |
| A | LEU388 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A 507 |
| Chain | Residue |
| A | TYR71 |
| A | ARG197 |
| A | THR384 |
| A | VAL424 |
| A | ASN425 |
| A | HOH736 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 508 |
| Chain | Residue |
| A | ASP208 |
| A | SER314 |
| A | PHE315 |
| A | HOH544 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. ILMHELNHAM |
| Chain | Residue | Details |
| A | ILE226-MET235 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17718519","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QN0","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17718519","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QN0","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1i1e |
| Chain | Residue | Details |
| A | TYR375 | |
| A | ARG372 | |
| A | GLU269 | |
