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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

3D7H

A high resolution crystal structure of human glutamate carboxypeptidase II (GCPII) in a complex with DCIBzL, a urea-based inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004180molecular_functioncarboxypeptidase activity
A0004181molecular_functionmetallocarboxypeptidase activity
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0006508biological_processproteolysis
A0006537biological_processglutamate biosynthetic process
A0006760biological_processfolic acid-containing compound metabolic process
A0008233molecular_functionpeptidase activity
A0008237molecular_functionmetallopeptidase activity
A0009986cellular_componentcell surface
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0016805molecular_functiondipeptidase activity
A0046872molecular_functionmetal ion binding
A0070062cellular_componentextracellular exosome
A0098829biological_processintestinal folate absorption
A1900451biological_processpositive regulation of glutamate receptor signaling pathway
A1904492molecular_functionAc-Asp-Glu binding
A1904493molecular_functiontetrahydrofolyl-poly(glutamate) polymer binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues313
DetailsRegion: {"description":"NAALADase"}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues1
DetailsActive site: {"description":"Nucleophile; for NAALADase activity"}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues3
DetailsActive site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RBU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RBU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CIJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OOT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RBU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues5
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z8L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CIJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OOT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RBU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues3
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"Q9Y3Q0","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues2
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ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues1
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ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues1
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ChainResidueDetails
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Number of Residues4
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ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15152093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z8L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CIJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OOT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RBU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15152093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z8L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C6P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CIJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OOT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RBU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15152093","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Z8L","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15152093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16467855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17372356","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17567119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18234225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19053759","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19301871","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C6C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CIJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OOT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XEJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BI1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BXM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3D7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IWW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RBU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3SJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JZ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LQG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4MCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NGS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OC5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OME","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P45","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P4J","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15152093","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1amp
ChainResidueDetails
AGLU424

243911

PDB entries from 2025-10-29

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