3D41

Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with MgAMPPNP and fosfomycin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004349	molecular_function	glutamate 5-kinase activity
A	0005829	cellular_component	cytosol
A	0016301	molecular_function	kinase activity
A	0102043	molecular_function	isopentenyl phosphate kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 267

Chain	Residue
A	HOH4002
A	HOH4003
A	HOH4004

---

site_id	AC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE ANP A 1260

Chain	Residue
A	THR170
A	ASP171
A	GLY174
A	ILE175
A	ALA200
A	LEU201
A	TRP202
A	ASP208
A	ALA212
A	MET213
A	LYS216
A	HOH4002
A	HOH4003
A	HOH4004
A	HOH4007
A	HOH4015
A	HOH4031
A	HOH4057
A	LYS9
A	GLY11
A	GLY12
A	SER13
A	LYS18
A	HIS58

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FCN A 4001

Chain	Residue
A	GLY52
A	GLY53
A	GLY57
A	SER148
A	SER149
A	THR210
A	HOH4004
A	HOH4010
A	HOH4031
A	HOH4057

---