3D41
Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with MgAMPPNP and fosfomycin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004349 | molecular_function | glutamate 5-kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006561 | biological_process | proline biosynthetic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0102043 | molecular_function | isopentenyl phosphate kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 267 |
| Chain | Residue |
| A | HOH4002 |
| A | HOH4003 |
| A | HOH4004 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ANP A 1260 |
| Chain | Residue |
| A | THR170 |
| A | ASP171 |
| A | GLY174 |
| A | ILE175 |
| A | ALA200 |
| A | LEU201 |
| A | TRP202 |
| A | ASP208 |
| A | ALA212 |
| A | MET213 |
| A | LYS216 |
| A | HOH4002 |
| A | HOH4003 |
| A | HOH4004 |
| A | HOH4007 |
| A | HOH4015 |
| A | HOH4031 |
| A | HOH4057 |
| A | LYS9 |
| A | GLY11 |
| A | GLY12 |
| A | SER13 |
| A | LYS18 |
| A | HIS58 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE FCN A 4001 |
| Chain | Residue |
| A | GLY52 |
| A | GLY53 |
| A | GLY57 |
| A | SER148 |
| A | SER149 |
| A | THR210 |
| A | HOH4004 |
| A | HOH4010 |
| A | HOH4031 |
| A | HOH4057 |
