Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0043892 | molecular_function | methylglyoxal reductase (NADPH) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0043892 | molecular_function | methylglyoxal reductase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NDP A 1 |
| Chain | Residue |
| A | GLY23 |
| A | GLN163 |
| A | TRP189 |
| A | SER190 |
| A | PRO191 |
| A | LEU192 |
| A | MET193 |
| A | GLN194 |
| A | LEU198 |
| A | ALA215 |
| A | ILE230 |
| A | VAL24 |
| A | PRO231 |
| A | LYS232 |
| A | SER233 |
| A | ILE234 |
| A | LYS235 |
| A | ARG238 |
| A | GLU241 |
| A | ASN242 |
| A | HOH284 |
| A | HOH296 |
| A | PHE25 |
| A | ASP49 |
| A | TYR54 |
| A | LYS79 |
| A | HIS112 |
| A | SER141 |
| A | ASN142 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NDP B 1 |
| Chain | Residue |
| B | GLY23 |
| B | VAL24 |
| B | PHE25 |
| B | ASP49 |
| B | TYR54 |
| B | LYS79 |
| B | HIS112 |
| B | SER141 |
| B | ASN142 |
| B | GLN163 |
| B | TRP189 |
| B | SER190 |
| B | PRO191 |
| B | LEU192 |
| B | MET193 |
| B | GLN194 |
| B | LEU198 |
| B | ILE230 |
| B | PRO231 |
| B | LYS232 |
| B | SER233 |
| B | ILE234 |
| B | LYS235 |
| B | ARG238 |
| B | ASN242 |
| B | HOH321 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. LeklykdgkIRAIGVSNF |
| Chain | Residue | Details |
| A | LEU126-PHE143 | |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. IPKSIKehRIiENaDI |
| Chain | Residue | Details |
| A | ILE230-ILE245 | |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRSIDTAaiyknEegVG |
| Chain | Residue | Details |
| A | GLY44-GLY61 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 106 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | TYR54 | |
| A | LYS79 | |
| A | ASP49 | |
| A | HIS112 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| B | TYR54 | |
| B | LYS79 | |
| B | ASP49 | |
| B | HIS112 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | TYR54 | |
| A | LYS79 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| B | TYR54 | |
| B | LYS79 | |
