3CWZ
Structure of RAB6(GTP)-R6IP1 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002080 | cellular_component | acrosomal membrane |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005802 | cellular_component | trans-Golgi network |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0006890 | biological_process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| A | 0006891 | biological_process | intra-Golgi vesicle-mediated transport |
| A | 0012505 | cellular_component | endomembrane system |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0018125 | biological_process | peptidyl-cysteine methylation |
| A | 0019882 | biological_process | antigen processing and presentation |
| A | 0019904 | molecular_function | protein domain specific binding |
| A | 0030667 | cellular_component | secretory granule membrane |
| A | 0031175 | biological_process | neuron projection development |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0031489 | molecular_function | myosin V binding |
| A | 0032588 | cellular_component | trans-Golgi network membrane |
| A | 0034067 | biological_process | protein localization to Golgi apparatus |
| A | 0034498 | biological_process | early endosome to Golgi transport |
| A | 0036064 | cellular_component | ciliary basal body |
| A | 0042147 | biological_process | retrograde transport, endosome to Golgi |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0070381 | cellular_component | endosome to plasma membrane transport vesicle |
| A | 0072385 | biological_process | minus-end-directed organelle transport along microtubule |
| A | 1903292 | biological_process | protein localization to Golgi membrane |
| B | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| B | 0031267 | molecular_function | small GTPase binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 302 |
| Chain | Residue |
| A | LYS26 |
| A | THR27 |
| A | THR45 |
| A | ASP68 |
| A | THR69 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE GTP A 4200 |
| Chain | Residue |
| A | THR27 |
| A | SER28 |
| A | PHE38 |
| A | ASN40 |
| A | TYR42 |
| A | GLN43 |
| A | ALA44 |
| A | THR45 |
| A | ALA70 |
| A | GLY71 |
| A | ASN126 |
| A | LYS127 |
| A | ASP129 |
| A | LEU130 |
| A | SER156 |
| A | ALA157 |
| A | LYS158 |
| A | GLN22 |
| A | SER23 |
| A | GLY25 |
| A | LYS26 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| A | SER23 | |
| A | ASP129 | |
| A | ALA157 | |
| A | LYS158 | |
| A | GLY25 | |
| A | LYS26 | |
| A | SER28 | |
| A | ASN40 | |
| A | TYR42 | |
| A | ASP68 | |
| A | GLY71 | |
| A | LYS127 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| A | VAL24 | |
| A | ASP39 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q6IQ26 |
| Chain | Residue | Details |
| A | THR27 | |
| A | THR45 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16332443, ECO:0000269|PubMed:19141279, ECO:0007744|PDB:2GIL, ECO:0007744|PDB:3CWZ |
| Chain | Residue | Details |
| A | ASN126 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ |
| Chain | Residue | Details |
| A | SER156 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: O-AMP-tyrosine; by Legionella DrrA => ECO:0000269|PubMed:21822290 |
| Chain | Residue | Details |
| A | TYR82 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P35279 |
| Chain | Residue | Details |
| A | SER184 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | LEU72 |
