3CWZ

Structure of RAB6(GTP)-R6IP1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0000166	molecular_function	nucleotide binding
A	0002080	cellular_component	acrosomal membrane
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005654	cellular_component	nucleoplasm
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0005802	cellular_component	trans-Golgi network
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006886	biological_process	intracellular protein transport
A	0006890	biological_process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A	0006891	biological_process	intra-Golgi vesicle-mediated transport
A	0012505	cellular_component	endomembrane system
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
A	0016787	molecular_function	hydrolase activity
A	0018125	biological_process	peptidyl-cysteine methylation
A	0019882	biological_process	antigen processing and presentation
A	0019904	molecular_function	protein domain specific binding
A	0030667	cellular_component	secretory granule membrane
A	0031175	biological_process	neuron projection development
A	0031410	cellular_component	cytoplasmic vesicle
A	0031489	molecular_function	myosin V binding
A	0032588	cellular_component	trans-Golgi network membrane
A	0034067	biological_process	protein localization to Golgi apparatus
A	0034498	biological_process	early endosome to Golgi transport
A	0036064	cellular_component	ciliary basal body
A	0042147	biological_process	retrograde transport, endosome to Golgi
A	0070062	cellular_component	extracellular exosome
A	0070381	cellular_component	endosome to plasma membrane transport vesicle
A	0072385	biological_process	minus-end-directed organelle transport along microtubule
A	1903292	biological_process	protein localization to Golgi membrane
B	0005085	molecular_function	guanyl-nucleotide exchange factor activity
B	0031267	molecular_function	small GTPase binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 302

Chain	Residue
A	LYS26
A	THR27
A	THR45
A	ASP68
A	THR69

---

site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GTP A 4200

Chain	Residue
A	THR27
A	SER28
A	PHE38
A	ASN40
A	TYR42
A	GLN43
A	ALA44
A	THR45
A	ALA70
A	GLY71
A	ASN126
A	LYS127
A	ASP129
A	LEU130
A	SER156
A	ALA157
A	LYS158
A	GLN22
A	SER23
A	GLY25
A	LYS26

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	19
Details	Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16034420","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18243103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YZQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BBP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16332443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19141279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CWZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"O-AMP-tyrosine; by Legionella DrrA","evidences":[{"source":"PubMed","id":"21822290","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	108
Details	Domain: {"description":"PLAT","evidences":[{"source":"PROSITE-ProRule","id":"PRU00152","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	LEU72

---