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3CVW

Drosophila melanogaster (6-4) photolyase H365N mutant bound to ds DNA with a T-T (6-4) photolesion and cofactor F0

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003677molecular_functionDNA binding
A0003904molecular_functiondeoxyribodipyrimidine photo-lyase activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0032922biological_processcircadian regulation of gene expression
A0043153biological_processentrainment of circadian clock by photoperiod
A0071949molecular_functionFAD binding
Functional Information from PDB Data
site_idAC1
Number of Residues22
DetailsBINDING SITE FOR RESIDUE FAD A 521
ChainResidue
APHE244
AARG303
ATYR306
ATRP362
AASN365
AARG368
AHIS369
AASP397
AGLN398
AASP399
ALEU402
ALYS246
AASN403
AASN406
ATRP407
ATHR258
ATHR259
ALEU261
ASER262
ALEU265
AGLN299
ATRP302

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE FO1 A 1422
ChainResidue
AARG13
ALYS14
APHE44
AILE45
ALEU46
AASP47
AILE50
AMET54
AARG60
AASP110
AGLU112
AARG118
ALYS266

Catalytic Information from CSA
site_idCSA1
Number of Residues3
DetailsAnnotated By Reference To The Literature 1dnp
ChainResidueDetails
ATRP384
ATRP407
ATRP330

224201

PDB entries from 2024-08-28

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