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3CUX

Atomic Resolution Structures of Escherichia coli and Bacillis anthracis Malate Synthase A: Comparison with Isoform G and Implications for Structure Based Drug Design

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004474molecular_functionmalate synthase activity
A0005737cellular_componentcytoplasm
A0006097biological_processglyoxylate cycle
A0006099biological_processtricarboxylic acid cycle
A0016746molecular_functionacyltransferase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 1
ChainResidue
AGLU247
AASP275
AHOH541
AHOH570
AHOH580

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 530
ChainResidue
AHOH678
AHOH695
ALEU153
AASN154
AASN286
AHIS287

Functional Information from PROSITE/UniProt
site_idPS00510
Number of Residues16
DetailsMALATE_SYNTHASE Malate synthase signature. KDHsaGLNcGrWDYIF
ChainResidueDetails
ALYS263-PHE278

Catalytic Information from CSA
site_idCSA1
Number of Residues4
DetailsAnnotated By Reference To The Literature 1d8c
ChainResidueDetails
AASP114
AGLU116
AASP443
AARG163

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PDB entries from 2024-10-30

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