3CUQ

Integrated structural and functional model of the human ESCRT-II complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000814	cellular_component	ESCRT II complex
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005667	cellular_component	transcription regulator complex
A	0005737	cellular_component	cytoplasm
A	0005768	cellular_component	endosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0008289	molecular_function	lipid binding
A	0010008	cellular_component	endosome membrane
A	0010628	biological_process	positive regulation of gene expression
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016236	biological_process	macroautophagy
A	0016247	molecular_function	channel regulator activity
A	0031902	cellular_component	late endosome membrane
A	0032456	biological_process	endocytic recycling
A	0036258	biological_process	multivesicular body assembly
A	0042176	biological_process	regulation of protein catabolic process
A	0042803	molecular_function	protein homodimerization activity
A	0043328	biological_process	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
A	0043405	biological_process	regulation of MAP kinase activity
A	0045022	biological_process	early endosome to late endosome transport
A	0045732	biological_process	positive regulation of protein catabolic process
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0055037	cellular_component	recycling endosome
A	0061635	biological_process	regulation of protein complex stability
A	0070062	cellular_component	extracellular exosome
A	0071985	biological_process	multivesicular body sorting pathway
A	0090148	biological_process	membrane fission
A	1903543	biological_process	positive regulation of exosomal secretion
B	0000814	cellular_component	ESCRT II complex
B	0032509	biological_process	endosome transport via multivesicular body sorting pathway
B	0043130	molecular_function	ubiquitin binding
C	0000814	cellular_component	ESCRT II complex
C	0005198	molecular_function	structural molecule activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005768	cellular_component	endosome
C	0005829	cellular_component	cytosol
C	0007175	biological_process	negative regulation of epidermal growth factor-activated receptor activity
C	0010008	cellular_component	endosome membrane
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0016236	biological_process	macroautophagy
C	0036258	biological_process	multivesicular body assembly
C	0042803	molecular_function	protein homodimerization activity
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0043328	biological_process	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
C	0070062	cellular_component	extracellular exosome
C	0071985	biological_process	multivesicular body sorting pathway
C	0090148	biological_process	membrane fission
D	0000814	cellular_component	ESCRT II complex
D	0005198	molecular_function	structural molecule activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005768	cellular_component	endosome
D	0005829	cellular_component	cytosol
D	0007175	biological_process	negative regulation of epidermal growth factor-activated receptor activity
D	0010008	cellular_component	endosome membrane
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0016236	biological_process	macroautophagy
D	0036258	biological_process	multivesicular body assembly
D	0042803	molecular_function	protein homodimerization activity
D	0043231	cellular_component	intracellular membrane-bounded organelle
D	0043328	biological_process	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
D	0070062	cellular_component	extracellular exosome
D	0071985	biological_process	multivesicular body sorting pathway
D	0090148	biological_process	membrane fission