Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0010815 | biological_process | bradykinin catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043069 | biological_process | negative regulation of programmed cell death |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070006 | molecular_function | metalloaminopeptidase activity |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 624 |
| Chain | Residue |
| A | ASP426 |
| A | HIS489 |
| A | GLU523 |
| A | GLU537 |
| A | HOH644 |
| A | HOH1519 |
| A | HOH1520 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 625 |
| Chain | Residue |
| A | ASP426 |
| A | THR428 |
| A | GLU537 |
| A | HOH644 |
| A | HOH1518 |
| A | PHE381 |
| A | ASP415 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 626 |
| Chain | Residue |
| A | ASP281 |
| A | THR435 |
| A | HOH658 |
| A | HOH670 |
| A | HOH717 |
| A | HOH739 |
| A | HOH752 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 627 |
| Chain | Residue |
| A | GLY486 |
| A | LYS507 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE P6G A 628 |
| Chain | Residue |
| A | PHE381 |
| A | ILE394 |
| A | HIS395 |
| A | HIS485 |
| A | GLY486 |
| A | HIS489 |
| A | HIS498 |
| A | GLU523 |
| A | HOH659 |
| A | HOH792 |
| A | HOH861 |
| A | HOH1298 |
| A | HOH1518 |
| A | HOH1520 |
Functional Information from PROSITE/UniProt
| site_id | PS00491 |
| Number of Residues | 13 |
| Details | PROLINE_PEPTIDASE Aminopeptidase P and proline dipeptidase signature. HGTGHgVGSfLNV |
| Chain | Residue | Details |
| A | HIS485-VAL497 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O44750","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18515364","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CTZ","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a16 |
| Chain | Residue | Details |
| A | GLU523 | |
| A | PRO501 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a16 |
| Chain | Residue | Details |
| A | GLU523 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a16 |
| Chain | Residue | Details |
| A | GLU523 | |
| A | HIS498 | |
