Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0045454 | biological_process | cell redox homeostasis |
A | 0098869 | biological_process | cellular oxidant detoxification |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0045454 | biological_process | cell redox homeostasis |
B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE FAD A 1000 |
Chain | Residue |
A | GLY23 |
A | THR54 |
A | ALA57 |
A | PRO58 |
A | LEU59 |
A | ASN62 |
A | THR121 |
A | THR122 |
A | GLY123 |
A | THR124 |
A | SER166 |
A | GLY25 |
A | GLN253 |
A | PHE256 |
A | GLY287 |
A | ASP288 |
A | ALA295 |
A | GLN296 |
A | ILE297 |
B | TYR34 |
A | ALA26 |
A | ALA27 |
A | LEU45 |
A | ASP46 |
A | LYS47 |
A | GLY52 |
A | LEU53 |
site_id | AC2 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE FAD B 1001 |
Chain | Residue |
A | TYR34 |
B | GLY23 |
B | GLY25 |
B | ALA26 |
B | ALA27 |
B | LEU45 |
B | ASP46 |
B | LYS47 |
B | GLY52 |
B | LEU53 |
B | THR54 |
B | ALA57 |
B | PRO58 |
B | ASN62 |
B | THR121 |
B | THR122 |
B | GLY123 |
B | SER166 |
B | GLN253 |
B | GLY287 |
B | ASP288 |
B | ALA295 |
B | GLN296 |
B | ILE297 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1tde |
Chain | Residue | Details |
A | CYS145 | |
A | CYS148 | |
A | ASP149 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1tde |
Chain | Residue | Details |
B | CYS145 | |
B | CYS148 | |
B | ASP149 | |