3CSQ

Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
A	0044423	cellular_component	virion component
A	0046718	biological_process	symbiont entry into host cell
A	0046872	molecular_function	metal ion binding
A	0071555	biological_process	cell wall organization
A	0098003	biological_process	viral tail assembly
A	0098004	biological_process	virus tail fiber assembly
A	0098023	cellular_component	virus tail, tip
A	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
A	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
A	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
B	0003824	molecular_function	catalytic activity
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0031640	biological_process	killing of cells of another organism
B	0042742	biological_process	defense response to bacterium
B	0044423	cellular_component	virion component
B	0046718	biological_process	symbiont entry into host cell
B	0046872	molecular_function	metal ion binding
B	0071555	biological_process	cell wall organization
B	0098003	biological_process	viral tail assembly
B	0098004	biological_process	virus tail fiber assembly
B	0098023	cellular_component	virus tail, tip
B	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
B	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
B	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
C	0003824	molecular_function	catalytic activity
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008237	molecular_function	metallopeptidase activity
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0031640	biological_process	killing of cells of another organism
C	0042742	biological_process	defense response to bacterium
C	0044423	cellular_component	virion component
C	0046718	biological_process	symbiont entry into host cell
C	0046872	molecular_function	metal ion binding
C	0071555	biological_process	cell wall organization
C	0098003	biological_process	viral tail assembly
C	0098004	biological_process	virus tail fiber assembly
C	0098023	cellular_component	virus tail, tip
C	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
C	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
C	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism
D	0003824	molecular_function	catalytic activity
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008237	molecular_function	metallopeptidase activity
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0031640	biological_process	killing of cells of another organism
D	0042742	biological_process	defense response to bacterium
D	0044423	cellular_component	virion component
D	0046718	biological_process	symbiont entry into host cell
D	0046872	molecular_function	metal ion binding
D	0071555	biological_process	cell wall organization
D	0098003	biological_process	viral tail assembly
D	0098004	biological_process	virus tail fiber assembly
D	0098023	cellular_component	virus tail, tip
D	0098932	biological_process	symbiont entry into host cell via disruption of host cell wall peptidoglycan
D	0098994	biological_process	symbiont entry into host cell via disruption of host cell envelope
D	0099002	biological_process	symbiont genome ejection through host cell envelope, short tail mechanism

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 335

Chain	Residue
D	HIS188
D	ASP195
D	HIS280
D	HOH371

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 335

Chain	Residue
C	HIS188
C	ASP195
C	HIS280
C	HOH355

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 335

Chain	Residue
B	ASP195
B	HIS280
B	HOH376
B	HIS188

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 335

Chain	Residue
A	HIS188
A	ASP195
A	HIS280
A	HOH359

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	632
Details	Region: {"description":"Lysozyme-like glycosidase"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"For lysozyme-like glycosidase activity","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CSZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CT0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CT1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CT5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CSQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---