3CRV
XPD_Helicase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003678 | molecular_function | DNA helicase activity |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006281 | biological_process | DNA repair |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016818 | molecular_function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0043139 | molecular_function | 5'-3' DNA helicase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0120545 | molecular_function | nucleic acid conformation isomerase activity |
| A | 0140097 | molecular_function | catalytic activity, acting on DNA |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FLC A 1900 |
| Chain | Residue |
| A | LYS369 |
| A | TYR473 |
| A | GLU496 |
| A | ARG531 |
| A | TRP537 |
| A | HOH717 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SF4 A 600 |
| Chain | Residue |
| A | CYS105 |
| A | LYS108 |
| A | CYS137 |
| A | CYS88 |
| A | ILE100 |
| A | CYS102 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IPA A 1804 |
| Chain | Residue |
| A | GLY32 |
| A | SER33 |
| A | GLY34 |
| A | LYS35 |
| A | THR36 |
| A | HOH845 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A 1806 |
| Chain | Residue |
| A | ASN21 |
| A | LYS530 |
| A | HOH826 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A 1807 |
| Chain | Residue |
| A | SER357 |
| A | TYR358 |
| A | LYS542 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A 1810 |
| Chain | Residue |
| A | HIS57 |
| A | GLY83 |
| A | THR155 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA A 1811 |
| Chain | Residue |
| A | SER368 |
| A | ILE471 |
| A | ARG531 |
| A | HOH614 |
| A | HOH701 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IPA A 1812 |
| Chain | Residue |
| A | ARG55 |
| A | ALA450 |
| A | GLU451 |
| A | GLY452 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2000 |
| Chain | Residue |
| A | ARG373 |
| A | PRO401 |
| A | SER402 |
| A | GLU404 |
| A | ILE405 |
| A | TYR473 |
| A | HOH680 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 227 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Motif: {"description":"DEAH box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18510924","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CRV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H8C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
