Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3CR4

X-ray structure of bovine Pnt,Ca(2+)-S100B

Functional Information from GO Data
ChainGOidnamespacecontents
X0005509molecular_functioncalcium ion binding
X0005515molecular_functionprotein binding
X0005576cellular_componentextracellular region
X0005615cellular_componentextracellular space
X0005634cellular_componentnucleus
X0005737cellular_componentcytoplasm
X0006417biological_processregulation of translation
X0007155biological_processcell adhesion
X0007409biological_processaxonogenesis
X0007611biological_processlearning or memory
X0008270molecular_functionzinc ion binding
X0008284biological_processpositive regulation of cell population proliferation
X0016310biological_processphosphorylation
X0019210molecular_functionkinase inhibitor activity
X0042803molecular_functionprotein homodimerization activity
X0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
X0044548molecular_functionS100 protein binding
X0045917biological_processpositive regulation of complement activation
X0046872molecular_functionmetal ion binding
X0048143biological_processastrocyte activation
X0048156molecular_functiontau protein binding
X0048306molecular_functioncalcium-dependent protein binding
X0050786molecular_functionRAGE receptor binding
X0071638biological_processnegative regulation of monocyte chemotactic protein-1 production
X0097490biological_processsympathetic neuron projection extension
X1990845biological_processadaptive thermogenesis
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE PNT X 101
ChainResidue
XMET0
XILE11
XASP12
XHIS15
XCYS84
XHIS85
XPHE87

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE PNT X 102
ChainResidue
XPHE43
XPHE88
XMET0
XHIS42

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA X 103
ChainResidue
XSER18
XGLU21
XASP23
XLYS26
XGLU31
XHOH105

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA X 104
ChainResidue
XASP61
XASP63
XASP65
XGLU67
XGLU72
XHOH112

Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DSDGDGECDfqEF
ChainResidueDetails
XASP61-PHE73

site_idPS00303
Number of Residues22
DetailsS100_CABP S-100/ICaBP type calcium binding protein signature. VMetLDsdgDgecDFqEFmaFV
ChainResidueDetails
XVAL56-VAL77

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues7
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P04271
ChainResidueDetails
XHIS15
XSER18
XGLU21
XASP23
XHIS25
XHIS85
XHIS90

site_idSWS_FT_FI2
Number of Residues5
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448
ChainResidueDetails
XASP61
XASP63
XASP65
XGLU67
XGLU72

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0000269|PubMed:4026304
ChainResidueDetails
XSER1

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon