3CQ5
Histidinol-phosphate aminotransferase from Corynebacterium glutamicum in complex with PMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0004400 | molecular_function | histidinol-phosphate transaminase activity |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0000105 | biological_process | L-histidine biosynthetic process |
| B | 0004400 | molecular_function | histidinol-phosphate transaminase activity |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0000105 | biological_process | L-histidine biosynthetic process |
| C | 0004400 | molecular_function | histidinol-phosphate transaminase activity |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | TYR21 |
| A | TYR123 |
| A | ASN172 |
| A | ARG333 |
| A | ARG342 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | ARG12 |
| A | GLU13 |
| B | ARG114 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 402 |
| Chain | Residue |
| B | TYR123 |
| B | ASN172 |
| B | ARG333 |
| B | ARG342 |
| B | TYR21 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 404 |
| Chain | Residue |
| A | ARG114 |
| B | GLU13 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 402 |
| Chain | Residue |
| C | TYR21 |
| C | TYR123 |
| C | ASN172 |
| C | ARG333 |
| C | ARG342 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 403 |
| Chain | Residue |
| C | ARG12 |
| C | GLU13 |
| C | ARG114 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 144 A 400 |
| Chain | Residue |
| A | THR34 |
| A | ASN99 |
| A | TYR123 |
| B | TYR63 |
| B | PRO256 |
| B | TYR257 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PMP A 401 |
| Chain | Residue |
| A | GLY97 |
| A | SER98 |
| A | ASN99 |
| A | TYR123 |
| A | THR168 |
| A | ASN172 |
| A | ASP197 |
| A | ALA199 |
| A | TYR200 |
| A | THR225 |
| A | SER227 |
| A | LYS228 |
| A | ARG236 |
| B | TYR63 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 144 A 405 |
| Chain | Residue |
| A | TYR63 |
| A | TYR257 |
| B | TYR21 |
| B | ALA23 |
| B | TYR123 |
| site_id | BC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PMP B 401 |
| Chain | Residue |
| A | TYR63 |
| B | GLY97 |
| B | SER98 |
| B | ASN99 |
| B | TYR123 |
| B | THR168 |
| B | ASN172 |
| B | ASP197 |
| B | ALA199 |
| B | TYR200 |
| B | THR225 |
| B | SER227 |
| B | LYS228 |
| B | ARG236 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 144 C 400 |
| Chain | Residue |
| C | TYR21 |
| C | ALA23 |
| C | THR34 |
| C | ASN99 |
| C | TYR123 |
| C | TYR257 |
| site_id | BC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PMP C 401 |
| Chain | Residue |
| C | TYR63 |
| C | GLY97 |
| C | SER98 |
| C | ASN99 |
| C | TYR123 |
| C | THR168 |
| C | ASN172 |
| C | ASP197 |
| C | ALA199 |
| C | TYR200 |
| C | THR225 |
| C | SER227 |
| C | LYS228 |
| C | ARG236 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01023","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| A | LYS228 | |
| A | TYR123 | |
| A | ASP197 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| B | LYS228 | |
| B | TYR123 | |
| B | ASP197 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| C | LYS228 | |
| C | TYR123 | |
| C | ASP197 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| A | TYR123 | |
| A | ASP197 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| B | TYR123 | |
| B | ASP197 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| C | TYR123 | |
| C | ASP197 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| A | ARG66 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| B | ARG66 |
| site_id | CSA9 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ay4 |
| Chain | Residue | Details |
| C | ARG66 |
