3CNK

Crystal Structure of the dimerization domain of human filamin A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0030036	biological_process	actin cytoskeleton organization
A	0051015	molecular_function	actin filament binding
B	0030036	biological_process	actin cytoskeleton organization
B	0051015	molecular_function	actin filament binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A2832

Chain	Residue
A	ALA2585
A	GLY2586
A	ASN2587
A	ASN2588
A	TRP2632

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B2833

Chain	Residue
B	TRP2632
B	HOH2794
B	HOH2798
B	ALA2585
B	GLY2586
B	ASN2587
B	ASN2588

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q8BTM8

Chain	Residue	Details
A	LYS2569
B	LYS2569

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8BTM8

Chain	Residue	Details
A	LYS2575
B	LYS2575

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8BTM8

Chain	Residue	Details
A	THR2599
B	THR2599

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS2607
A	LYS2621
B	LYS2607
B	LYS2621

---