3CMU

Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000725	biological_process	recombinational repair
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003697	molecular_function	single-stranded DNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006259	biological_process	DNA metabolic process
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0006974	biological_process	DNA damage response
A	0008094	molecular_function	ATP-dependent activity, acting on DNA
A	0009355	cellular_component	DNA polymerase V complex
A	0009432	biological_process	SOS response
A	0010212	biological_process	response to ionizing radiation
A	0016887	molecular_function	ATP hydrolysis activity
A	0019985	biological_process	translesion synthesis
A	0035825	biological_process	homologous recombination
A	0048870	biological_process	cell motility
A	0140297	molecular_function	DNA-binding transcription factor binding
A	0140664	molecular_function	ATP-dependent DNA damage sensor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 500

Chain	Residue
A	THR73
A	GLU96
A	ASP144
A	LYS1250

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ALF A 501

Chain	Residue
A	PHE1217
A	LYS1248
A	LYS1250
A	GLU68
A	SER69
A	LYS72
A	THR73
A	GLU96

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1500

Chain	Residue
A	THR1073
A	GLU1096
A	LYS2250

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ALF A 1501

Chain	Residue
A	GLU1068
A	SER1069
A	LYS1072
A	THR1073
A	GLU1096
A	PHE2217
A	LYS2248
A	LYS2250

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 2500

Chain	Residue
A	THR2073
A	GLU2096
A	LYS3250

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ALF A 2501

Chain	Residue
A	GLU2068
A	SER2069
A	LYS2072
A	THR2073
A	GLU2096
A	PHE3217
A	LYS3248
A	LYS3250

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 3500

Chain	Residue
A	THR3073
A	GLU3096
A	LYS4250

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ALF A 3501

Chain	Residue
A	GLU3068
A	SER3069
A	LYS3072
A	THR3073
A	GLU3096
A	PHE4217
A	LYS4248
A	LYS4250

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 4500

Chain	Residue
A	THR4073
A	GLU4096
A	LYS5250

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ALF A 4501

Chain	Residue
A	GLU4068
A	SER4069
A	LYS4072
A	THR4073
A	GLU4096
A	PHE5217
A	LYS5248
A	LYS5250

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 5500

Chain	Residue
A	THR5073
A	GLU5096

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ALF A 5501

Chain	Residue
A	GLU5068
A	SER5069
A	LYS5072
A	THR5073
A	GLU5096

---

site_id	BC4
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 502

Chain	Residue
A	SER69
A	SER70
A	GLY71
A	LYS72
A	THR73
A	THR74
A	ASP100
A	TYR103
A	SER240
A	TYR264
A	ASN1249
A	LYS1250
A	ILE1251
A	ALA1252
A	ALA1253
A	PRO1254

---

site_id	BC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 1502

Chain	Residue
A	SER1069
A	SER1070
A	GLY1071
A	LYS1072
A	THR1073
A	THR1074
A	ASP1100
A	TYR1103
A	SER1240
A	TYR1264
A	ASN2249
A	LYS2250
A	ILE2251
A	ALA2252
A	ALA2253
A	PRO2254

---

site_id	BC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ADP A 2502

Chain	Residue
A	GLY2071
A	LYS2072
A	THR2073
A	THR2074
A	ASP2100
A	TYR2103
A	SER2240
A	TYR2264
A	ASN3249
A	LYS3250
A	ILE3251
A	ALA3252
A	ALA3253
A	PRO3254
A	PRO2067
A	GLU2068
A	SER2069
A	SER2070

---

site_id	BC7
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 3502

Chain	Residue
A	SER3069
A	SER3070
A	GLY3071
A	LYS3072
A	THR3073
A	THR3074
A	ASP3100
A	TYR3103
A	SER3240
A	TYR3264
A	ASN4249
A	LYS4250
A	ILE4251
A	ALA4252
A	ALA4253
A	PRO4254

---

site_id	BC8
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 4502

Chain	Residue
A	SER4069
A	SER4070
A	GLY4071
A	LYS4072
A	THR4073
A	THR4074
A	ASP4100
A	TYR4103
A	SER4240
A	TYR4264
A	ASN5249
A	LYS5250
A	ILE5251
A	ALA5252
A	ALA5253
A	PRO5254

---

site_id	BC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ADP A 5502

Chain	Residue
A	GLU5068
A	SER5069
A	SER5070
A	GLY5071
A	LYS5072
A	THR5073
A	THR5074
A	ASP5100
A	TYR5103
A	SER5240
A	TYR5264

---

Functional Information from PROSITE/UniProt

site_id	PS00321
Number of Residues	9
Details	RECA_1 recA signature. ALKFYASVR

Chain	Residue	Details
A	ALA214-ARG222
A	ALA1214-ARG1222
A	ALA2214-ARG2222
A	ALA3214-ARG3222
A	ALA4214-ARG4222
A	ALA5214-ARG5222

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00268, ECO:0000269|PubMed:1731253

Chain	Residue	Details
A	GLY5066

---