3CMI

Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0004602	molecular_function	glutathione peroxidase activity
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005777	cellular_component	peroxisome
A	0005782	cellular_component	peroxisomal matrix
A	0005829	cellular_component	cytosol
A	0006979	biological_process	response to oxidative stress
A	0034599	biological_process	cellular response to oxidative stress
A	0047066	molecular_function	phospholipid-hydroperoxide glutathione peroxidase activity
A	0098869	biological_process	cellular oxidant detoxification
A	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity

Functional Information from PROSITE/UniProt

site_id	PS00460
Number of Residues	16
Details	GLUTATHIONE_PEROXID_1 Glutathione peroxidases active site. GKvVLIvNVaSkCGfT

Chain	Residue	Details
A	GLY24-THR39

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site_id	PS00763
Number of Residues	8
Details	GLUTATHIONE_PEROXID_2 Glutathione peroxidases signature 2. IGFPCNQF

Chain	Residue	Details
A	ILE60-PHE67

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000269|PubMed:17720812, ECO:0000305|PubMed:18767166

Chain	Residue	Details
A	CYS36

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1gp1

Chain	Residue	Details
A	TRP125

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