3CKL
Crystal structure of human cytosolic sulfotransferase SULT1B1 in complex with PAP and resveratrol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004062 | molecular_function | aryl sulfotransferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006068 | biological_process | ethanol catabolic process |
| A | 0006576 | biological_process | biogenic amine metabolic process |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0008146 | molecular_function | sulfotransferase activity |
| A | 0009812 | biological_process | flavonoid metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018958 | biological_process | phenol-containing compound metabolic process |
| A | 0030855 | biological_process | epithelial cell differentiation |
| A | 0042403 | biological_process | thyroid hormone metabolic process |
| A | 0050427 | biological_process | 3'-phosphoadenosine 5'-phosphosulfate metabolic process |
| A | 0051923 | biological_process | sulfation |
| B | 0004062 | molecular_function | aryl sulfotransferase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006068 | biological_process | ethanol catabolic process |
| B | 0006576 | biological_process | biogenic amine metabolic process |
| B | 0006805 | biological_process | xenobiotic metabolic process |
| B | 0008146 | molecular_function | sulfotransferase activity |
| B | 0009812 | biological_process | flavonoid metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0018958 | biological_process | phenol-containing compound metabolic process |
| B | 0030855 | biological_process | epithelial cell differentiation |
| B | 0042403 | biological_process | thyroid hormone metabolic process |
| B | 0050427 | biological_process | 3'-phosphoadenosine 5'-phosphosulfate metabolic process |
| B | 0051923 | biological_process | sulfation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE STL A 501 |
| Chain | Residue |
| A | THR21 |
| A | PHE24 |
| A | MET81 |
| A | LEU86 |
| A | HIS109 |
| A | PHE143 |
| A | GLN150 |
| A | TYR170 |
| A | LEU244 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE STL B 501 |
| Chain | Residue |
| B | THR21 |
| B | PHE24 |
| B | MET81 |
| B | HIS109 |
| B | PHE143 |
| B | ASN147 |
| B | GLN150 |
| B | TYR170 |
| B | LEU244 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE A3P A 601 |
| Chain | Residue |
| A | LYS48 |
| A | SER49 |
| A | GLY50 |
| A | THR51 |
| A | THR52 |
| A | TRP53 |
| A | ARG131 |
| A | SER139 |
| A | TYR194 |
| A | THR228 |
| A | SER229 |
| A | PHE230 |
| A | MET233 |
| A | PHE256 |
| A | MET257 |
| A | ARG258 |
| A | LYS259 |
| A | GLY260 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE A3P B 601 |
| Chain | Residue |
| B | LYS48 |
| B | SER49 |
| B | GLY50 |
| B | THR51 |
| B | THR52 |
| B | TRP53 |
| B | ARG131 |
| B | SER139 |
| B | TYR194 |
| B | THR228 |
| B | SER229 |
| B | PHE230 |
| B | MET233 |
| B | PHE256 |
| B | MET257 |
| B | ARG258 |
| B | LYS259 |
| B | GLY260 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS109 | |
| B | HIS109 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16804942, ECO:0000269|Ref.8, ECO:0007744|PDB:2Z5F, ECO:0007744|PDB:3CKL |
| Chain | Residue | Details |
| A | LYS48 | |
| B | TYR194 | |
| B | THR228 | |
| B | ARG258 | |
| A | ARG131 | |
| A | SER139 | |
| A | TYR194 | |
| A | THR228 | |
| A | ARG258 | |
| B | LYS48 | |
| B | ARG131 | |
| B | SER139 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS107 | |
| B | LYS107 |
