3CJQ

Ribosomal protein L11 methyltransferase (PrmA) in complex with dimethylated ribosomal protein L11 in space group P212121

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006479	biological_process	protein methylation
A	0008168	molecular_function	methyltransferase activity
A	0008276	molecular_function	protein methyltransferase activity
A	0016279	molecular_function	protein-lysine N-methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0032259	biological_process	methylation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0015934	cellular_component	large ribosomal subunit
B	0019843	molecular_function	rRNA binding
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	0070180	molecular_function	large ribosomal subunit rRNA binding
B	1990904	cellular_component	ribonucleoprotein complex
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006479	biological_process	protein methylation
D	0008168	molecular_function	methyltransferase activity
D	0008276	molecular_function	protein methyltransferase activity
D	0016279	molecular_function	protein-lysine N-methyltransferase activity
D	0016740	molecular_function	transferase activity
D	0032259	biological_process	methylation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005515	molecular_function	protein binding
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015934	cellular_component	large ribosomal subunit
E	0019843	molecular_function	rRNA binding
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	0070180	molecular_function	large ribosomal subunit rRNA binding
E	1990904	cellular_component	ribonucleoprotein complex
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0006479	biological_process	protein methylation
G	0008168	molecular_function	methyltransferase activity
G	0008276	molecular_function	protein methyltransferase activity
G	0016279	molecular_function	protein-lysine N-methyltransferase activity
G	0016740	molecular_function	transferase activity
G	0032259	biological_process	methylation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015934	cellular_component	large ribosomal subunit
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0070180	molecular_function	large ribosomal subunit rRNA binding
H	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 148

Chain	Residue
B	LYS2

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD H 148

Chain	Residue
H	LYS2

---

site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH A 303

Chain	Residue
A	ASP149
A	ILE150
A	GLY174
A	SER175
A	ASN191
A	LEU192
A	LEU196
A	HOH306
A	HOH368
B	2MM1
A	PHE99
A	GLY100
A	THR107
A	GLY128
A	THR129
A	GLY130
A	LEU134

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 2MM B 1

Chain	Residue
A	THR106
A	ASN191
A	LEU192
A	GLY218
A	SAH303
B	LYS2
B	LYS3

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAH D 303

Chain	Residue
A	GLU48
D	PHE99
D	GLY100
D	THR107
D	GLY128
D	THR129
D	LEU134
D	ASP149
D	ILE150
D	SER175
D	ASN191
D	LEU192
D	LEU196
D	HOH328
D	HOH329
D	HOH350
E	2MM1
E	HOH152

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 2MM E 1

Chain	Residue
D	THR106
D	ASN191
D	LEU192
D	GLY218
D	LEU220
D	TRP247
D	SAH303
E	LYS2
E	LYS3

---

site_id	AC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE SAH G 303

Chain	Residue
G	PHE99
G	GLY100
G	THR107
G	GLY128
G	THR129
G	LEU134
G	ASP149
G	ILE150
G	ASP151
G	GLY174
G	SER175
G	ASN191
G	LEU192
G	LEU196
H	2MM1

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 2MM H 1

Chain	Residue
G	THR106
G	ASN191
G	LEU192
G	GLY218
G	TRP247
G	SAH303
H	LYS2
H	LYS3

---

Functional Information from PROSITE/UniProt

site_id	PS00359
Number of Residues	16
Details	RIBOSOMAL_L11 Ribosomal protein L11 signature. RmIaGSarSMGvEVvG

Chain	Residue	Details
B	ARG125-GLY140

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00735","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17215866","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611379","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2007","submissionDatabase":"PDB data bank","title":"Crystal structure of ribosomal protein L11 methyltransferase from Thermus thermophilus.","authors":["Kaminishi T.","Sakai H.","Takemoto-Hori C.","Terada T.","Nakagawa N.","Maoka N.","Kuramitsu S.","Shirouzu M.","Yokoyama S."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17215866","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611379","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2007","submissionDatabase":"PDB data bank","title":"Crystal structure of ribosomal protein L11 methyltransferase from Thermus thermophilus.","authors":["Kaminishi T.","Sakai H.","Takemoto-Hori C.","Terada T.","Nakagawa N.","Maoka N.","Kuramitsu S.","Shirouzu M.","Yokoyama S."]}}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1qam

Chain	Residue	Details
A	ASP149
A	ASN191
A	GLY128

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1qam

Chain	Residue	Details
D	ASP149
D	ASN191
D	GLY128

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1qam

Chain	Residue	Details
G	ASP149
G	ASN191
G	GLY128

---