3CJQ
Ribosomal protein L11 methyltransferase (PrmA) in complex with dimethylated ribosomal protein L11 in space group P212121
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006338 | biological_process | chromatin remodeling |
| A | 0006479 | biological_process | protein methylation |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008276 | molecular_function | protein methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0042054 | molecular_function | histone methyltransferase activity |
| B | 0003735 | molecular_function | structural constituent of ribosome |
| B | 0005515 | molecular_function | protein binding |
| B | 0005840 | cellular_component | ribosome |
| B | 0006412 | biological_process | translation |
| B | 0019843 | molecular_function | rRNA binding |
| B | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| B | 0070180 | molecular_function | large ribosomal subunit rRNA binding |
| B | 1990904 | cellular_component | ribonucleoprotein complex |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006338 | biological_process | chromatin remodeling |
| D | 0006479 | biological_process | protein methylation |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0008276 | molecular_function | protein methyltransferase activity |
| D | 0032259 | biological_process | methylation |
| D | 0042054 | molecular_function | histone methyltransferase activity |
| E | 0003735 | molecular_function | structural constituent of ribosome |
| E | 0005515 | molecular_function | protein binding |
| E | 0005840 | cellular_component | ribosome |
| E | 0006412 | biological_process | translation |
| E | 0019843 | molecular_function | rRNA binding |
| E | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| E | 0070180 | molecular_function | large ribosomal subunit rRNA binding |
| E | 1990904 | cellular_component | ribonucleoprotein complex |
| G | 0005515 | molecular_function | protein binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006338 | biological_process | chromatin remodeling |
| G | 0006479 | biological_process | protein methylation |
| G | 0008168 | molecular_function | methyltransferase activity |
| G | 0008276 | molecular_function | protein methyltransferase activity |
| G | 0032259 | biological_process | methylation |
| G | 0042054 | molecular_function | histone methyltransferase activity |
| H | 0003735 | molecular_function | structural constituent of ribosome |
| H | 0005515 | molecular_function | protein binding |
| H | 0005840 | cellular_component | ribosome |
| H | 0006412 | biological_process | translation |
| H | 0019843 | molecular_function | rRNA binding |
| H | 0022625 | cellular_component | cytosolic large ribosomal subunit |
| H | 0070180 | molecular_function | large ribosomal subunit rRNA binding |
| H | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD B 148 |
| Chain | Residue |
| B | LYS2 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD H 148 |
| Chain | Residue |
| H | LYS2 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE SAH A 303 |
| Chain | Residue |
| A | ASP149 |
| A | ILE150 |
| A | GLY174 |
| A | SER175 |
| A | ASN191 |
| A | LEU192 |
| A | LEU196 |
| A | HOH306 |
| A | HOH368 |
| B | 2MM1 |
| A | PHE99 |
| A | GLY100 |
| A | THR107 |
| A | GLY128 |
| A | THR129 |
| A | GLY130 |
| A | LEU134 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2MM B 1 |
| Chain | Residue |
| A | THR106 |
| A | ASN191 |
| A | LEU192 |
| A | GLY218 |
| A | SAH303 |
| B | LYS2 |
| B | LYS3 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE SAH D 303 |
| Chain | Residue |
| A | GLU48 |
| D | PHE99 |
| D | GLY100 |
| D | THR107 |
| D | GLY128 |
| D | THR129 |
| D | LEU134 |
| D | ASP149 |
| D | ILE150 |
| D | SER175 |
| D | ASN191 |
| D | LEU192 |
| D | LEU196 |
| D | HOH328 |
| D | HOH329 |
| D | HOH350 |
| E | 2MM1 |
| E | HOH152 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2MM E 1 |
| Chain | Residue |
| D | THR106 |
| D | ASN191 |
| D | LEU192 |
| D | GLY218 |
| D | LEU220 |
| D | TRP247 |
| D | SAH303 |
| E | LYS2 |
| E | LYS3 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE SAH G 303 |
| Chain | Residue |
| G | PHE99 |
| G | GLY100 |
| G | THR107 |
| G | GLY128 |
| G | THR129 |
| G | LEU134 |
| G | ASP149 |
| G | ILE150 |
| G | ASP151 |
| G | GLY174 |
| G | SER175 |
| G | ASN191 |
| G | LEU192 |
| G | LEU196 |
| H | 2MM1 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2MM H 1 |
| Chain | Residue |
| G | THR106 |
| G | ASN191 |
| G | LEU192 |
| G | GLY218 |
| G | TRP247 |
| G | SAH303 |
| H | LYS2 |
| H | LYS3 |
Functional Information from PROSITE/UniProt
| site_id | PS00359 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L11 Ribosomal protein L11 signature. RmIaGSarSMGvEVvG |
| Chain | Residue | Details |
| B | ARG125-GLY140 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00735, ECO:0000269|PubMed:17215866, ECO:0000269|PubMed:18611379, ECO:0000269|Ref.6 |
| Chain | Residue | Details |
| A | THR107 | |
| G | GLY128 | |
| G | ASP149 | |
| G | ASN191 | |
| A | GLY128 | |
| A | ASP149 | |
| A | ASN191 | |
| D | THR107 | |
| D | GLY128 | |
| D | ASP149 | |
| D | ASN191 | |
| G | THR107 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17215866, ECO:0000269|PubMed:18611379, ECO:0000269|Ref.6 |
| Chain | Residue | Details |
| A | SER175 | |
| D | SER175 | |
| G | SER175 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qam |
| Chain | Residue | Details |
| A | ASP149 | |
| A | ASN191 | |
| A | GLY128 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qam |
| Chain | Residue | Details |
| D | ASP149 | |
| D | ASN191 | |
| D | GLY128 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qam |
| Chain | Residue | Details |
| G | ASP149 | |
| G | ASN191 | |
| G | GLY128 |
