3CIX

X-RAY structure of the [FeFe]-hydrogenase maturase HydE from thermotoga maritima in complex with thiocyanate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SCN A 1712

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL A 1713

Chain	Residue
A	HOH2825
A	ARG159
A	THR268
A	THR269
A	ALA270
A	TYR306
A	HOH2802

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1714

Chain	Residue
A	ARG159
A	HOH2604
A	HOH2826

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SF4 A 2460

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	GLY109

---

site_id	AC5
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SAH A 1501

Chain	Residue
A	TYR69
A	SER108
A	SER136
A	ARG159
A	GLU161
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	TYR306
A	HOH2472
A	HOH2478
A	HOH2480
A	HOH2489
A	HOH2526
A	HOH2802

---

site_id	AC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE CPS A 1701

Chain	Residue
A	GLN98
A	PHE99
A	GLY100
A	GLU280
A	ARG284
A	MET324
A	LEU329
A	LEU330
A	HOH2469
A	HOH2504
A	HOH2554
A	HOH2566
A	HOH2684
A	HOH2774
A	HOH2793

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SAT A 1722

Chain	Residue
A	LYS170
A	SER297
A	LYS315
A	ASP316

---

site_id	AC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CPS A 1702

Chain	Residue
A	LYS37
A	ASP40
A	ARG284
A	THR317
A	HOH2551
A	HOH2558
A	HOH2608
A	HOH2636
A	HOH2655
A	HOH2661

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CPS A 1703

Chain	Residue
A	ARG29
A	GLU33
A	PHE246
A	THR247
A	LEU250
A	HOH2553
A	HOH2557
A	HOH2563

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CPS A 1704

Chain	Residue
A	ARG29
A	LYS315
A	THR317
A	ALA318
A	HOH2592
A	HOH2686
A	HOH2689
A	HOH2758

---

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE CPS A 1705

Chain	Residue
A	LYS128
A	MET324
A	LYS325
A	GLU328
A	HOH2669
A	HOH2702
A	HOH2736
A	HOH2737
A	HOH2774

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FES A 1707

Chain	Residue
A	ARG279
A	CYS311
A	CYS319
A	CYS322
A	HOH2461

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG A 1706

Chain	Residue
A	ASP337
A	TRP338
A	GLY339
A	GLY340
A	LYS342

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1716

Chain	Residue
A	LYS243
A	GLY244
A	ASP245
A	PHE246
A	HOH2542

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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