3CIW

X-RAY structure of the [FeFe]-hydrogenase maturase HydE from thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CL A 349

Chain	Residue
A	ARG159
A	THR268
A	THR269
A	ALA270
A	TYR306
A	HOH2811
A	HOH2812

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 350

Chain	Residue
A	ARG155
A	ARG54
A	THR134

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 351

Chain	Residue
A	ARG159
A	PRO266
A	MET291
A	HOH2603

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SF4 A 2460

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	GLY109

---

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH A 1501

Chain	Residue
A	TYR69
A	SER108
A	SER136
A	ARG159
A	GLU161
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	HOH2471
A	HOH2477
A	HOH2479
A	HOH2488
A	HOH2527
A	HOH2794

---

site_id	AC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE CPS A 1701

Chain	Residue
A	GLN98
A	PHE99
A	GLY100
A	PRO276
A	GLY277
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	HOH2468
A	HOH2504
A	HOH2554
A	HOH2565
A	HOH2685
A	HOH2753
A	HOH2773
A	HOH2820

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SAT A 1706

Chain	Residue
A	LYS170
A	SER297
A	ASP316
A	HOH2781

---

site_id	AC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CPS A 1702

Chain	Residue
A	LYS37
A	ASP40
A	ARG284
A	THR317
A	HOH2558
A	HOH2607
A	HOH2634
A	HOH2653
A	HOH2659
A	HOH2781

---

site_id	AC9
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CPS A 1703

Chain	Residue
A	ARG29
A	GLU33
A	PHE246
A	THR247
A	LEU250
A	HOH2553
A	HOH2557
A	HOH2563
A	HOH2758
A	HOH2775
A	HOH2824

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CPS A 1704

Chain	Residue
A	ARG29
A	THR317
A	ALA318
A	HOH2563
A	HOH2591
A	HOH2688
A	HOH2821
A	HOH2835

---

site_id	BC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE CPS A 1705

Chain	Residue
A	LYS128
A	MET324
A	LYS325
A	GLU328
A	HOH2667
A	HOH2703
A	HOH2741
A	HOH2742
A	HOH2773

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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