3CIS
The Crystal Structure of Rv2623 from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001666 | biological_process | response to hypoxia |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0040008 | biological_process | regulation of growth |
| A | 0085014 | biological_process | dormancy entry of symbiont in host |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0001666 | biological_process | response to hypoxia |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0040008 | biological_process | regulation of growth |
| B | 0085014 | biological_process | dormancy entry of symbiont in host |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0001666 | biological_process | response to hypoxia |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C | 0040008 | biological_process | regulation of growth |
| C | 0085014 | biological_process | dormancy entry of symbiont in host |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0001666 | biological_process | response to hypoxia |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0009274 | cellular_component | peptidoglycan-based cell wall |
| D | 0040008 | biological_process | regulation of growth |
| D | 0085014 | biological_process | dormancy entry of symbiont in host |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0001666 | biological_process | response to hypoxia |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005829 | cellular_component | cytosol |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0009274 | cellular_component | peptidoglycan-based cell wall |
| E | 0040008 | biological_process | regulation of growth |
| E | 0085014 | biological_process | dormancy entry of symbiont in host |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0001666 | biological_process | response to hypoxia |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005829 | cellular_component | cytosol |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0009274 | cellular_component | peptidoglycan-based cell wall |
| F | 0040008 | biological_process | regulation of growth |
| F | 0085014 | biological_process | dormancy entry of symbiont in host |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0001666 | biological_process | response to hypoxia |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005829 | cellular_component | cytosol |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0009274 | cellular_component | peptidoglycan-based cell wall |
| G | 0040008 | biological_process | regulation of growth |
| G | 0085014 | biological_process | dormancy entry of symbiont in host |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0001666 | biological_process | response to hypoxia |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005829 | cellular_component | cytosol |
| H | 0005886 | cellular_component | plasma membrane |
| H | 0009274 | cellular_component | peptidoglycan-based cell wall |
| H | 0040008 | biological_process | regulation of growth |
| H | 0085014 | biological_process | dormancy entry of symbiont in host |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG A 1002 |
| Chain | Residue |
| A | ASP198 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG C 1002 |
| Chain | Residue |
| C | ASP198 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG D 2002 |
| Chain | Residue |
| D | ASP198 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG E 1002 |
| Chain | Residue |
| E | ASP198 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG F 2002 |
| Chain | Residue |
| F | ASP198 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG G 1002 |
| Chain | Residue |
| G | ASP198 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP A 1101 |
| Chain | Residue |
| A | SER17 |
| A | ALA20 |
| A | ALA43 |
| A | GLY117 |
| A | LEU119 |
| A | GLY120 |
| A | SER121 |
| A | GLY122 |
| A | ARG123 |
| A | ARG127 |
| A | GLY130 |
| A | SER131 |
| A | SER133 |
| A | GLY13 |
| A | ILE14 |
| A | ASP15 |
| site_id | BC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP A 1102 |
| Chain | Residue |
| A | GLY165 |
| A | ASP167 |
| A | SER172 |
| A | LEU193 |
| A | ALA195 |
| A | ASP198 |
| A | PRO245 |
| A | GLY262 |
| A | ARG264 |
| A | GLY265 |
| A | ARG266 |
| A | GLY267 |
| A | GLY268 |
| A | MET272 |
| A | GLY275 |
| A | SER276 |
| A | GLY278 |
| site_id | BC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ATP B 2101 |
| Chain | Residue |
| B | GLY13 |
| B | ILE14 |
| B | ASP15 |
| B | SER17 |
| B | ALA20 |
| B | ALA43 |
| B | ALA100 |
| B | LEU104 |
| B | GLY117 |
| B | LEU119 |
| B | GLY120 |
| B | SER121 |
| B | GLY122 |
| B | ARG123 |
| B | ARG127 |
| B | GLY130 |
| B | SER131 |
| B | SER133 |
| site_id | BC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP B 2102 |
| Chain | Residue |
| B | GLY165 |
| B | ASP167 |
| B | SER172 |
| B | LEU193 |
| B | ALA195 |
| B | ASP198 |
| B | PRO245 |
| B | GLY262 |
| B | ARG264 |
| B | GLY265 |
| B | ARG266 |
| B | GLY267 |
| B | GLY268 |
| B | MET272 |
| B | GLY275 |
| B | SER276 |
| B | GLY278 |
| site_id | BC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP C 1101 |
| Chain | Residue |
| C | GLY13 |
| C | ILE14 |
| C | ASP15 |
| C | SER17 |
| C | ALA20 |
| C | ALA43 |
| C | GLY117 |
| C | LEU119 |
| C | GLY120 |
| C | SER121 |
| C | GLY122 |
| C | ARG123 |
| C | ARG127 |
| C | GLY130 |
| C | SER131 |
| C | SER133 |
| site_id | BC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP C 1102 |
| Chain | Residue |
| C | ARG264 |
| C | GLY265 |
| C | GLY267 |
| C | GLY268 |
| C | MET272 |
| C | GLY275 |
| C | SER276 |
| C | GLY278 |
| C | GLY165 |
| C | ASP167 |
| C | SER172 |
| C | LEU193 |
| C | HIS194 |
| C | ALA195 |
| C | ASP198 |
| C | PRO245 |
| C | GLY262 |
| site_id | BC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ATP D 2101 |
| Chain | Residue |
| D | GLY13 |
| D | ILE14 |
| D | ASP15 |
| D | SER17 |
| D | ALA20 |
| D | ALA43 |
| D | ALA100 |
| D | LEU104 |
| D | GLY117 |
| D | LEU119 |
| D | GLY120 |
| D | SER121 |
| D | GLY122 |
| D | ARG123 |
| D | ARG127 |
| D | GLY130 |
| D | SER131 |
| D | SER133 |
| site_id | BC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP D 2102 |
| Chain | Residue |
| D | GLY165 |
| D | ASP167 |
| D | LEU193 |
| D | ALA195 |
| D | ASP198 |
| D | PRO245 |
| D | GLY262 |
| D | ARG264 |
| D | GLY265 |
| D | ARG266 |
| D | GLY267 |
| D | GLY268 |
| D | MET272 |
| D | GLY275 |
| D | SER276 |
| D | GLY278 |
| site_id | BC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP E 1101 |
| Chain | Residue |
| E | GLY13 |
| E | ILE14 |
| E | ASP15 |
| E | SER17 |
| E | ALA20 |
| E | ALA43 |
| E | GLY117 |
| E | LEU119 |
| E | GLY120 |
| E | SER121 |
| E | GLY122 |
| E | ARG123 |
| E | ARG127 |
| E | GLY130 |
| E | SER131 |
| E | SER133 |
| site_id | BC9 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP E 1102 |
| Chain | Residue |
| E | GLY165 |
| E | ASP167 |
| E | SER172 |
| E | LEU193 |
| E | ALA195 |
| E | ASP198 |
| E | PRO245 |
| E | GLY262 |
| E | ARG264 |
| E | GLY265 |
| E | GLY267 |
| E | GLY268 |
| E | MET272 |
| E | GLY275 |
| E | SER276 |
| E | GLY278 |
| site_id | CC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ATP F 2101 |
| Chain | Residue |
| F | GLY13 |
| F | ILE14 |
| F | ASP15 |
| F | SER17 |
| F | ALA43 |
| F | GLY117 |
| F | LEU119 |
| F | GLY120 |
| F | SER121 |
| F | GLY122 |
| F | ARG123 |
| F | ARG127 |
| F | GLY130 |
| F | SER131 |
| F | SER133 |
| site_id | CC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP F 2102 |
| Chain | Residue |
| F | GLY165 |
| F | ASP167 |
| F | LEU193 |
| F | ALA195 |
| F | ASP198 |
| F | PRO245 |
| F | GLY262 |
| F | ARG264 |
| F | GLY265 |
| F | ARG266 |
| F | GLY267 |
| F | GLY268 |
| F | MET272 |
| F | GLY275 |
| F | SER276 |
| F | GLY278 |
| site_id | CC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ATP G 1101 |
| Chain | Residue |
| G | GLY13 |
| G | ILE14 |
| G | ASP15 |
| G | SER17 |
| G | ALA20 |
| G | ALA43 |
| G | GLY117 |
| G | LEU119 |
| G | GLY120 |
| G | SER121 |
| G | GLY122 |
| G | ARG123 |
| G | ARG127 |
| G | GLY130 |
| G | SER131 |
| G | SER133 |
| site_id | CC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ATP G 1102 |
| Chain | Residue |
| G | GLY165 |
| G | ASP167 |
| G | SER172 |
| G | LEU193 |
| G | HIS194 |
| G | ALA195 |
| G | ASP198 |
| G | PRO245 |
| G | GLY262 |
| G | ARG264 |
| G | GLY265 |
| G | ARG266 |
| G | GLY267 |
| G | GLY268 |
| G | MET272 |
| G | GLY275 |
| G | SER276 |
| G | GLY278 |
| site_id | CC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP H 2101 |
| Chain | Residue |
| H | GLY13 |
| H | ILE14 |
| H | ASP15 |
| H | SER17 |
| H | ALA20 |
| H | ALA43 |
| H | ALA100 |
| H | GLY117 |
| H | LEU119 |
| H | GLY120 |
| H | SER121 |
| H | GLY122 |
| H | ARG123 |
| H | ARG127 |
| H | GLY130 |
| H | SER131 |
| H | SER133 |
| site_id | CC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP H 2102 |
| Chain | Residue |
| H | GLY165 |
| H | ASP167 |
| H | SER172 |
| H | LEU193 |
| H | ALA195 |
| H | ASP198 |
| H | PRO245 |
| H | GLY262 |
| H | ARG264 |
| H | GLY265 |
| H | ARG266 |
| H | GLY267 |
| H | GLY268 |
| H | MET272 |
| H | GLY275 |
| H | SER276 |
| H | GLY278 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 160 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of universal stress protein Rv2623 from mycobacterium tuberculosis.","authoringGroup":["Mycobacterium tuberculosis structural genomics consortium (TB)"]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2008","submissionDatabase":"PDB data bank","title":"The crystal structure of Rv2623: a novel, tandem-repeat universal stress protein of Mycobacterium tuberculosis.","authors":["Drumm J.","Mi K.","Bilder P.","Almo S.","Chan J."]}},{"source":"PDB","id":"2JAX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
