3CH2

Crystal Structure Analysis of SERA5E from plasmodium falciparum

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0006508	biological_process	proteolysis
X	0008234	molecular_function	cysteine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA X 1

Chain	Residue
X	ASP757
X	ASP758
X	HOH886
X	HOH887
X	HOH888
X	HOH954
X	HOH956

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Functional Information from PROSITE/UniProt

site_id	PS00639
Number of Residues	11
Details	THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. ADHAVNIVGYG

Chain	Residue	Details
X	ALA760-GLY770

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site_id	PS00640
Number of Residues	20
Details	THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvRNSWgpyWGdeGYFkV

Chain	Residue	Details
X	TYR782-VAL801

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10089

Chain	Residue	Details
X	HIS762

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10090

Chain	Residue	Details
X	ASN787

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Ancestral active site => ECO:0000305|PubMed:19591843, ECO:0000305|PubMed:25599609

Chain	Residue	Details
X	SER596

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
X	ASN828

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 9pap

Chain	Residue	Details
X	HIS762
X	GLN590
X	ASN787

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site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 9pap

Chain	Residue	Details
X	HIS762
X	GLN590
X	ASN787
X	SER596

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