3CDO
Bacteriophage T4 lysozyme mutant R96V in wildtype background at low temperature
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0044659 | biological_process | viral release from host cell by cytolysis |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0044659 | biological_process | viral release from host cell by cytolysis |
| C | 0003796 | molecular_function | lysozyme activity |
| C | 0009253 | biological_process | peptidoglycan catabolic process |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0016998 | biological_process | cell wall macromolecule catabolic process |
| C | 0030430 | cellular_component | host cell cytoplasm |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0042742 | biological_process | defense response to bacterium |
| C | 0044659 | biological_process | viral release from host cell by cytolysis |
| D | 0003796 | molecular_function | lysozyme activity |
| D | 0009253 | biological_process | peptidoglycan catabolic process |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0016998 | biological_process | cell wall macromolecule catabolic process |
| D | 0030430 | cellular_component | host cell cytoplasm |
| D | 0031640 | biological_process | killing of cells of another organism |
| D | 0042742 | biological_process | defense response to bacterium |
| D | 0044659 | biological_process | viral release from host cell by cytolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1902 |
| Chain | Residue |
| A | ARG125 |
| B | SER38 |
| B | LEU39 |
| B | ASN40 |
| B | HOH2014 |
| B | HOH2033 |
| B | HOH2047 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1903 |
| Chain | Residue |
| B | PHE114 |
| B | THR115 |
| B | ASN116 |
| B | SER117 |
| B | HOH1955 |
| B | SER44 |
| B | LYS48 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1905 |
| Chain | Residue |
| B | THR142 |
| B | PRO143 |
| B | ASN144 |
| B | ARG145 |
| B | HOH2052 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1906 |
| Chain | Residue |
| C | SER44 |
| C | LYS48 |
| C | PHE114 |
| C | THR115 |
| C | ASN116 |
| C | SER117 |
| C | ASN132 |
| C | HOH2136 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1901 |
| Chain | Residue |
| C | SER38 |
| C | LEU39 |
| C | ASN40 |
| D | ARG125 |
| D | HOH2136 |
| D | HOH2146 |
| D | HOH2160 |
| D | HOH2170 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1904 |
| Chain | Residue |
| D | THR142 |
| D | PRO143 |
| D | ASN144 |
| D | ARG145 |
| D | HOH2128 |
| D | HOH2133 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE HEZ A 1901 |
| Chain | Residue |
| A | ASP89 |
| A | SER90 |
| A | LYS124 |
| A | HOH2103 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HEZ C 1921 |
| Chain | Residue |
| C | LEU33 |
| C | HEZ1922 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE HEZ C 1922 |
| Chain | Residue |
| C | LYS35 |
| C | MET106 |
| C | HEZ1921 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HEZ D 1923 |
| Chain | Residue |
| D | ASP89 |
| D | LYS124 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD A 1911 |
| Chain | Residue |
| A | ASP72 |
| A | ARG76 |
| A | HOH2064 |
| B | ILE3 |
| B | VAL75 |
| B | TYR88 |
| B | HOH1970 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD A 1914 |
| Chain | Residue |
| A | TYR88 |
| A | HOH1927 |
| A | HOH2068 |
| B | ASP72 |
| B | ARG76 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MPD D 1912 |
| Chain | Residue |
| C | ASP72 |
| C | ARG76 |
| D | TYR88 |
| D | HOH2052 |
| D | HOH2060 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD D 1913 |
| Chain | Residue |
| C | TYR88 |
| C | HOH2144 |
| D | VAL71 |
| D | ASP72 |
| D | ARG76 |
| D | HOH2186 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | GLU11 | |
| B | GLU11 | |
| C | GLU11 | |
| D | GLU11 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | ASP20 | |
| B | ASP20 | |
| C | ASP20 | |
| D | ASP20 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | LEU32 | |
| A | PHE104 | |
| B | LEU32 | |
| B | PHE104 | |
| C | LEU32 | |
| C | PHE104 | |
| D | LEU32 | |
| D | PHE104 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000303|PubMed:7831309 |
| Chain | Residue | Details |
| A | SER117 | |
| A | ASN132 | |
| B | SER117 | |
| B | ASN132 | |
| C | SER117 | |
| C | ASN132 | |
| D | SER117 | |
| D | ASN132 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| A | GLU11 | |
| A | ASP20 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| B | GLU11 | |
| B | ASP20 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| C | GLU11 | |
| C | ASP20 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 206l |
| Chain | Residue | Details |
| D | GLU11 | |
| D | ASP20 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| A | GLU11 | proton shuttle (general acid/base) |
| A | ASP20 | covalent catalysis |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| B | GLU11 | proton shuttle (general acid/base) |
| B | ASP20 | covalent catalysis |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| C | GLU11 | proton shuttle (general acid/base) |
| C | ASP20 | covalent catalysis |
| site_id | MCSA4 |
| Number of Residues | 2 |
| Details | M-CSA 921 |
| Chain | Residue | Details |
| D | GLU11 | proton shuttle (general acid/base) |
| D | ASP20 | covalent catalysis |
