3CB4

The Crystal Structure of LepA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003746	molecular_function	translation elongation factor activity
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006412	biological_process	translation
A	0006414	biological_process	translational elongation
A	0009268	biological_process	response to pH
A	0009409	biological_process	response to cold
A	0009651	biological_process	response to salt stress
A	0016787	molecular_function	hydrolase activity
A	0042274	biological_process	ribosomal small subunit biogenesis
A	0042802	molecular_function	identical protein binding
A	0043022	molecular_function	ribosome binding
A	0043023	molecular_function	ribosomal large subunit binding
A	0043024	molecular_function	ribosomal small subunit binding
A	0045727	biological_process	positive regulation of translation
A	0097216	molecular_function	guanosine tetraphosphate binding
B	0000166	molecular_function	nucleotide binding
B	0003746	molecular_function	translation elongation factor activity
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006412	biological_process	translation
B	0006414	biological_process	translational elongation
B	0009268	biological_process	response to pH
B	0009409	biological_process	response to cold
B	0009651	biological_process	response to salt stress
B	0016787	molecular_function	hydrolase activity
B	0042274	biological_process	ribosomal small subunit biogenesis
B	0042802	molecular_function	identical protein binding
B	0043022	molecular_function	ribosome binding
B	0043023	molecular_function	ribosomal large subunit binding
B	0043024	molecular_function	ribosomal small subunit binding
B	0045727	biological_process	positive regulation of translation
B	0097216	molecular_function	guanosine tetraphosphate binding
C	0000166	molecular_function	nucleotide binding
C	0003746	molecular_function	translation elongation factor activity
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006412	biological_process	translation
C	0006414	biological_process	translational elongation
C	0009268	biological_process	response to pH
C	0009409	biological_process	response to cold
C	0009651	biological_process	response to salt stress
C	0016787	molecular_function	hydrolase activity
C	0042274	biological_process	ribosomal small subunit biogenesis
C	0042802	molecular_function	identical protein binding
C	0043022	molecular_function	ribosome binding
C	0043023	molecular_function	ribosomal large subunit binding
C	0043024	molecular_function	ribosomal small subunit binding
C	0045727	biological_process	positive regulation of translation
C	0097216	molecular_function	guanosine tetraphosphate binding
D	0000166	molecular_function	nucleotide binding
D	0003746	molecular_function	translation elongation factor activity
D	0003924	molecular_function	GTPase activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006412	biological_process	translation
D	0006414	biological_process	translational elongation
D	0009268	biological_process	response to pH
D	0009409	biological_process	response to cold
D	0009651	biological_process	response to salt stress
D	0016787	molecular_function	hydrolase activity
D	0042274	biological_process	ribosomal small subunit biogenesis
D	0042802	molecular_function	identical protein binding
D	0043022	molecular_function	ribosome binding
D	0043023	molecular_function	ribosomal large subunit binding
D	0043024	molecular_function	ribosomal small subunit binding
D	0045727	biological_process	positive regulation of translation
D	0097216	molecular_function	guanosine tetraphosphate binding
E	0000166	molecular_function	nucleotide binding
E	0003746	molecular_function	translation elongation factor activity
E	0003924	molecular_function	GTPase activity
E	0005515	molecular_function	protein binding
E	0005525	molecular_function	GTP binding
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006412	biological_process	translation
E	0006414	biological_process	translational elongation
E	0009268	biological_process	response to pH
E	0009409	biological_process	response to cold
E	0009651	biological_process	response to salt stress
E	0016787	molecular_function	hydrolase activity
E	0042274	biological_process	ribosomal small subunit biogenesis
E	0042802	molecular_function	identical protein binding
E	0043022	molecular_function	ribosome binding
E	0043023	molecular_function	ribosomal large subunit binding
E	0043024	molecular_function	ribosomal small subunit binding
E	0045727	biological_process	positive regulation of translation
E	0097216	molecular_function	guanosine tetraphosphate binding
F	0000166	molecular_function	nucleotide binding
F	0003746	molecular_function	translation elongation factor activity
F	0003924	molecular_function	GTPase activity
F	0005515	molecular_function	protein binding
F	0005525	molecular_function	GTP binding
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006412	biological_process	translation
F	0006414	biological_process	translational elongation
F	0009268	biological_process	response to pH
F	0009409	biological_process	response to cold
F	0009651	biological_process	response to salt stress
F	0016787	molecular_function	hydrolase activity
F	0042274	biological_process	ribosomal small subunit biogenesis
F	0042802	molecular_function	identical protein binding
F	0043022	molecular_function	ribosome binding
F	0043023	molecular_function	ribosomal large subunit binding
F	0043024	molecular_function	ribosomal small subunit binding
F	0045727	biological_process	positive regulation of translation
F	0097216	molecular_function	guanosine tetraphosphate binding

Functional Information from PROSITE/UniProt

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DSmdlEReRGITIkaQ

Chain	Residue	Details
D	ASP42-GLN57

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00071","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
D	HIS81

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site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	HIS81

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site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	HIS81

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site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	HIS81

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site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
E	HIS81

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site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
F	HIS81

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