Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000774 | molecular_function | adenyl-nucleotide exchange factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005516 | molecular_function | calmodulin binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006457 | biological_process | protein folding |
| A | 0006914 | biological_process | autophagy |
| A | 0010499 | biological_process | proteasomal ubiquitin-independent protein catabolic process |
| A | 0042026 | biological_process | protein refolding |
| A | 0042277 | molecular_function | peptide binding |
| A | 0043161 | biological_process | proteasome-mediated ubiquitin-dependent protein catabolic process |
| A | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
| B | 0005524 | molecular_function | ATP binding |
| B | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG A 667 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 555 |
| Chain | Residue |
| B | ALA191 |
| B | ARG193 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 556 |
| Chain | Residue |
| A | ASP474 |
| B | ARG236 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 558 |
| Chain | Residue |
| B | THR13 |
| B | LYS71 |
| B | THR204 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 668 |
| Chain | Residue |
| A | ASN13 |
| A | LYS276 |
| A | ASN12 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 559 |
| Chain | Residue |
| A | ASN33 |
| A | LYS54 |
| B | ARG269 |
| B | ARG272 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 669 |
| Chain | Residue |
| A | ASP25 |
| A | ILE26 |
| A | ARG34 |
| B | LYS25 |
| B | ARG36 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 670 |
| Chain | Residue |
| A | SER181 |
| A | PHE185 |
| A | LEU366 |
| A | ASN367 |
| A | LYS374 |
| B | GLU27 |
| B | TYR134 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BEF A 671 |
| Chain | Residue |
| A | ASP8 |
| A | GLY10 |
| A | ASP203 |
| A | ILE372 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP A 672 |
| Chain | Residue |
| A | GLY10 |
| A | ASN11 |
| A | ASN12 |
| A | ASN13 |
| A | GLY205 |
| A | HIS206 |
| A | GLU272 |
| A | LYS275 |
| A | LYS276 |
| A | SER279 |
| A | GLY343 |
| A | THR344 |
| A | ARG346 |
| A | ILE347 |
| B | GLN33 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP B 560 |
| Chain | Residue |
| A | SER32 |
| B | GLY201 |
| B | GLY202 |
| B | GLY230 |
| B | GLU268 |
| B | LYS271 |
| B | ARG272 |
| B | SER275 |
| B | GLY338 |
| B | GLY339 |
| B | SER340 |
| B | ARG342 |
| B | ILE343 |
| B | ASP366 |
Functional Information from PROSITE/UniProt
| site_id | PS00297 |
| Number of Residues | 8 |
| Details | HSP70_1 Heat shock hsp70 proteins family signature 1. IDLGTTyS |
| Chain | Residue | Details |
| B | ILE9-SER16 | |
| site_id | PS00329 |
| Number of Residues | 14 |
| Details | HSP70_2 Heat shock hsp70 proteins family signature 2. IFDLGGGTfdvSIL |
| Chain | Residue | Details |
| B | ILE197-LEU210 | |
| A | PHE201-MET214 | |
| site_id | PS01036 |
| Number of Residues | 15 |
| Details | HSP70_3 Heat shock hsp70 proteins family signature 3. IvLvGGsTRIPkIqK |
| Chain | Residue | Details |
| B | ILE334-LYS348 | |
| A | VAL338-GLN352 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | GLY12 | |
| B | LYS71 | |
| Chain | Residue | Details |
| B | THR14 | |
| B | TYR15 | |
| B | GLY202 | |
| B | GLU268 | |
| B | LYS271 | |
| B | SER275 | |
| B | GLY339 | |
| Chain | Residue | Details |
| B | LYS108 | |
| B | LYS328 | |
| B | LYS524 | |
| Chain | Residue | Details |
| B | SER153 | |
| B | SER329 | |
| B | SER362 | |
| B | SER541 | |
| Chain | Residue | Details |
| B | LYS246 | |
| Chain | Residue | Details |
| B | LYS319 | |
| B | LYS512 | |
| Chain | Residue | Details |
| B | ARG469 | |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:P11142 |
| Chain | Residue | Details |
| B | LYS512 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 656 |
| Chain | Residue | Details |
| B | ASP10 | |
| B | LYS71 | enhance reactivity |
| B | GLU175 | |
| B | ASP199 | |
