3C7A

A structural basis for substrate and stereo selectivity in octopine dehydrogenase (ODH-NADH)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0047830	molecular_function	D-octopine dehydrogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAD A 405

Chain	Residue
A	GLY10
A	CYS148
A	HIS403
A	HOH425
A	HOH437
A	HOH441
A	HOH625
A	HOH633
A	HOH645
A	HOH672
A	HOH688
A	GLY11
A	ASN12
A	GLY13
A	PHE35
A	GLU38
A	PRO91
A	LEU144
A	ALA147

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 406

Chain	Residue
A	GLU142
A	MET206
A	TYR208
A	TRP278
A	HIS404
A	HOH846

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 407

Chain	Residue
A	ASP108
A	LYS132

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 408

Chain	Residue
A	GLU142
A	GLU202

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 409

Chain	Residue
A	HOH757

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 411

Chain	Residue
A	ALA312
A	HOH465
A	HOH814

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 412

Chain	Residue
A	LYS172
A	GLY173
A	HOH496
A	HOH676

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 414

Chain	Residue
A	SER182
A	GLN185

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 415

Chain	Residue
A	LEU181
A	GLN185
A	PHE194

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PubMed","id":"18599075","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18599075","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20808820","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18599075","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20808820","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1bg6

Chain	Residue	Details
A	HIS212
A	ASP329

---