3C77

1.08 A crystal structure of nitrophorin 4 from Rhodnius prolixus containing FE(III) deuteroporphyrin ix complexed with ammonia at ph 7.5

Replaces:  2AT4

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005576	cellular_component	extracellular region
X	0016491	molecular_function	oxidoreductase activity
X	0042311	biological_process	vasodilation
X	0046872	molecular_function	metal ion binding
X	0051381	molecular_function	histamine binding
X	0070026	molecular_function	nitric oxide binding
X	0097746	biological_process	blood vessel diameter maintenance

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NH3 X 700

Chain	Residue
X	LEU133
X	HOH777
X	HOH858

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site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE FDE X 185

Chain	Residue
X	LYS88
X	TYR105
X	LEU123
X	LYS125
X	LYS128
X	LEU133
X	HOH873
X	PRO37
X	TYR40
X	LEU57
X	HIS59
X	ASP70
X	PHE86

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"10876239","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11560480","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14673714","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16171383","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20524697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334402","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22976968","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23474537","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9782054","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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