3C6B

Reaction product of paraoxon and S-formylglutathione hydrolase W197I mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0018738	molecular_function	S-formylglutathione hydrolase activity
A	0046294	biological_process	formaldehyde catabolic process
A	0046872	molecular_function	metal ion binding
A	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from PROSITE/UniProt

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. VAITGHSMGG

Chain	Residue	Details
A	VAL155-GLY164

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:P10768

Chain	Residue	Details
A	SDP161
A	ASP241
A	HIS276

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:22906720, ECO:0007744|PDB:4FLM

Chain	Residue	Details
A	MET1
A	HIS140

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