3C6B

Reaction product of paraoxon and S-formylglutathione hydrolase W197I mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0018738	molecular_function	S-formylglutathione hydrolase activity
A	0046294	biological_process	formaldehyde catabolic process
A	0046872	molecular_function	metal ion binding
A	0052689	molecular_function	carboxylic ester hydrolase activity

Functional Information from PROSITE/UniProt

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. VAITGHSMGG

Chain	Residue	Details
A	VAL155-GLY164

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"P10768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22906720","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FLM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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