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3C2X

Crystal structure of peptidoglycan recognition protein at 1.8A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0001818biological_processnegative regulation of cytokine production
A0005576cellular_componentextracellular region
A0008270molecular_functionzinc ion binding
A0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
A0009253biological_processpeptidoglycan catabolic process
A0016019molecular_functionpeptidoglycan immune receptor activity
A0016045biological_processdetection of bacterium
A0042742biological_processdefense response to bacterium
A0042834molecular_functionpeptidoglycan binding
A0045087biological_processinnate immune response
A0050830biological_processdefense response to Gram-positive bacterium
B0001818biological_processnegative regulation of cytokine production
B0005576cellular_componentextracellular region
B0008270molecular_functionzinc ion binding
B0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
B0009253biological_processpeptidoglycan catabolic process
B0016019molecular_functionpeptidoglycan immune receptor activity
B0016045biological_processdetection of bacterium
B0042742biological_processdefense response to bacterium
B0042834molecular_functionpeptidoglycan binding
B0045087biological_processinnate immune response
B0050830biological_processdefense response to Gram-positive bacterium
C0001818biological_processnegative regulation of cytokine production
C0005576cellular_componentextracellular region
C0008270molecular_functionzinc ion binding
C0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
C0009253biological_processpeptidoglycan catabolic process
C0016019molecular_functionpeptidoglycan immune receptor activity
C0016045biological_processdetection of bacterium
C0042742biological_processdefense response to bacterium
C0042834molecular_functionpeptidoglycan binding
C0045087biological_processinnate immune response
C0050830biological_processdefense response to Gram-positive bacterium
D0001818biological_processnegative regulation of cytokine production
D0005576cellular_componentextracellular region
D0008270molecular_functionzinc ion binding
D0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
D0009253biological_processpeptidoglycan catabolic process
D0016019molecular_functionpeptidoglycan immune receptor activity
D0016045biological_processdetection of bacterium
D0042742biological_processdefense response to bacterium
D0042834molecular_functionpeptidoglycan binding
D0045087biological_processinnate immune response
D0050830biological_processdefense response to Gram-positive bacterium
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 D 502
ChainResidue
CTRP66
DPRO96
DTHR97
DGLN150

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE TLA C 6748
ChainResidue
DHIS37
DALA39
DTHR152
DLEU153
DSER154
CHIS37
CALA39
CTHR152
CLEU153
CSER154

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL A 172
ChainResidue
AGLY40
ASER41
AGLN52
AASN55

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE GOL B 172
ChainResidue
BGLY40
BSER41
BGLN52
BASN55

site_idAC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL C 6749
ChainResidue
CHIS42
CARG114

site_idAC6
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL C 6750
ChainResidue
CLYS90
CGLY95
CPRO96
CASN99
CPRO100
DPRO96

site_idAC7
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL C 6751
ChainResidue
CTYR32
CTRP98

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL D 503
ChainResidue
CPRO151
CTHR152
DHIS37
DALA39
DTYR71
DHIS146

site_idAC9
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL A 173
ChainResidue
ASER139
AHIS168

site_idBC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 174
ChainResidue
AARG25
AGLU83
AASN88

site_idBC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL D 504
ChainResidue
CPRO96
DLYS90
DGLY95
DPRO96
DASN99

site_idBC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL A 175
ChainResidue
ALYS90
APRO96
AASN99

site_idBC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE GOL D 505
ChainResidue
DARG147
DLEU153
DASP157

site_idBC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL D 506
ChainResidue
AASN113
DARG170

site_idBC6
Number of Residues1
DetailsBINDING SITE FOR RESIDUE GOL D 507
ChainResidue
DHIS42

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PDB entries from 2024-07-24

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