3C2X
Crystal structure of peptidoglycan recognition protein at 1.8A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001818 | biological_process | negative regulation of cytokine production |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008745 | molecular_function | N-acetylmuramoyl-L-alanine amidase activity |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016019 | molecular_function | peptidoglycan immune receptor activity |
| A | 0016045 | biological_process | detection of bacterium |
| A | 0042834 | molecular_function | peptidoglycan binding |
| A | 0045087 | biological_process | innate immune response |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0001818 | biological_process | negative regulation of cytokine production |
| B | 0005576 | cellular_component | extracellular region |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008745 | molecular_function | N-acetylmuramoyl-L-alanine amidase activity |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016019 | molecular_function | peptidoglycan immune receptor activity |
| B | 0016045 | biological_process | detection of bacterium |
| B | 0042834 | molecular_function | peptidoglycan binding |
| B | 0045087 | biological_process | innate immune response |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
| C | 0001818 | biological_process | negative regulation of cytokine production |
| C | 0005576 | cellular_component | extracellular region |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0008745 | molecular_function | N-acetylmuramoyl-L-alanine amidase activity |
| C | 0009253 | biological_process | peptidoglycan catabolic process |
| C | 0016019 | molecular_function | peptidoglycan immune receptor activity |
| C | 0016045 | biological_process | detection of bacterium |
| C | 0042834 | molecular_function | peptidoglycan binding |
| C | 0045087 | biological_process | innate immune response |
| C | 0050830 | biological_process | defense response to Gram-positive bacterium |
| D | 0001818 | biological_process | negative regulation of cytokine production |
| D | 0005576 | cellular_component | extracellular region |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0008745 | molecular_function | N-acetylmuramoyl-L-alanine amidase activity |
| D | 0009253 | biological_process | peptidoglycan catabolic process |
| D | 0016019 | molecular_function | peptidoglycan immune receptor activity |
| D | 0016045 | biological_process | detection of bacterium |
| D | 0042834 | molecular_function | peptidoglycan binding |
| D | 0045087 | biological_process | innate immune response |
| D | 0050830 | biological_process | defense response to Gram-positive bacterium |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 502 |
| Chain | Residue |
| C | TRP66 |
| D | PRO96 |
| D | THR97 |
| D | GLN150 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE TLA C 6748 |
| Chain | Residue |
| D | HIS37 |
| D | ALA39 |
| D | THR152 |
| D | LEU153 |
| D | SER154 |
| C | HIS37 |
| C | ALA39 |
| C | THR152 |
| C | LEU153 |
| C | SER154 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 172 |
| Chain | Residue |
| A | GLY40 |
| A | SER41 |
| A | GLN52 |
| A | ASN55 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 172 |
| Chain | Residue |
| B | GLY40 |
| B | SER41 |
| B | GLN52 |
| B | ASN55 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 6749 |
| Chain | Residue |
| C | HIS42 |
| C | ARG114 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 6750 |
| Chain | Residue |
| C | LYS90 |
| C | GLY95 |
| C | PRO96 |
| C | ASN99 |
| C | PRO100 |
| D | PRO96 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 6751 |
| Chain | Residue |
| C | TYR32 |
| C | TRP98 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 503 |
| Chain | Residue |
| C | PRO151 |
| C | THR152 |
| D | HIS37 |
| D | ALA39 |
| D | TYR71 |
| D | HIS146 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 173 |
| Chain | Residue |
| A | SER139 |
| A | HIS168 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 174 |
| Chain | Residue |
| A | ARG25 |
| A | GLU83 |
| A | ASN88 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 504 |
| Chain | Residue |
| C | PRO96 |
| D | LYS90 |
| D | GLY95 |
| D | PRO96 |
| D | ASN99 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 175 |
| Chain | Residue |
| A | LYS90 |
| A | PRO96 |
| A | ASN99 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 505 |
| Chain | Residue |
| D | ARG147 |
| D | LEU153 |
| D | ASP157 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL D 506 |
| Chain | Residue |
| A | ASN113 |
| D | ARG170 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL D 507 |
| Chain | Residue |
| D | HIS42 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 512 |
| Details | Domain: {"description":"N-acetylmuramoyl-L-alanine amidase","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
