3C2F

Crystal structure of the quinolinate phosphoribosyl transferase (BNA6) from Saccharomyces cerevisiae complexed with PRPP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004514	molecular_function	nicotinate-nucleotide diphosphorylase (carboxylating) activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0009435	biological_process	NAD biosynthetic process
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0034213	biological_process	quinolinate catabolic process
A	0034354	biological_process	'de novo' NAD biosynthetic process from tryptophan

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:18321072

Chain	Residue	Details
A	ARG107
A	ARG166
A	LYS176
A	ASP227

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
A	SER256
A	THR142

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	GLU206

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	1
Details	M-CSA 945

Chain	Residue	Details
A	LYS144	electrostatic stabiliser

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