3BX7
Engineered Human Lipocalin 2 (LCN2) in Complex with the Extracellular Domain of Human CTLA-4
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 14 |
| Details | LIPOCALIN Lipocalin signature. NFQdnQFHGKWYVV |
| Chain | Residue | Details |
| A | ASN21-VAL34 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 101 |
| Details | Domain: {"description":"Ig-like V-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Region: {"description":"Homodimerization","evidences":[{"source":"PubMed","id":"21156796","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Region: {"description":"Important for interaction with CD80 and CD86","evidences":[{"source":"PubMed","id":"28484017","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | Region: {"description":"Homodimerization","evidences":[{"source":"PubMed","id":"21156796","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28484017","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"11279502","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16002699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21156796","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"11279502","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16002699","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
