3BVW
GOLGI MANNOSIDASE II D204A catalytic nucleophile mutant complex with Methyl (2-deoxy-2-acetamido-beta-D-glucopyranosyl)-(1->2)-ALPHA-D-mannopyranosyl- (1->3)-[ALPHA-D-mannopyranosyl-(1->6)-6-thio-alpha-D-mannopyranosyl- (1->6)]-BETA-D-mannopyranoside
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000139 | cellular_component | Golgi membrane |
A | 0003824 | molecular_function | catalytic activity |
A | 0004559 | molecular_function | alpha-mannosidase activity |
A | 0004572 | molecular_function | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity |
A | 0005783 | cellular_component | endoplasmic reticulum |
A | 0005794 | cellular_component | Golgi apparatus |
A | 0005795 | cellular_component | Golgi stack |
A | 0005975 | biological_process | carbohydrate metabolic process |
A | 0006013 | biological_process | mannose metabolic process |
A | 0006486 | biological_process | protein glycosylation |
A | 0006491 | biological_process | N-glycan processing |
A | 0015923 | molecular_function | mannosidase activity |
A | 0016020 | cellular_component | membrane |
A | 0016063 | biological_process | rhodopsin biosynthetic process |
A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
A | 0030246 | molecular_function | carbohydrate binding |
A | 0035010 | biological_process | encapsulation of foreign target |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Nucleophile => ECO:0000250 |
Chain | Residue | Details |
A | ALA204 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | HIS90 | |
A | ASP92 | |
A | ALA204 | |
A | HIS471 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 793 |
Chain | Residue | Details |
A | HIS90 | metal ligand |
A | ASP92 | metal ligand |
A | ALA204 | covalently attached, metal ligand, nucleofuge, nucleophile |
A | ASP341 | activator, increase nucleophilicity, proton acceptor, proton donor |
A | HIS471 | metal ligand |