3BVF
Structural basis for the iron uptake mechanism of Helicobacter pylori ferritin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004322 | molecular_function | ferroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0008198 | molecular_function | ferrous iron binding |
| A | 0008199 | molecular_function | ferric iron binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004322 | molecular_function | ferroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006826 | biological_process | iron ion transport |
| B | 0006879 | biological_process | intracellular iron ion homeostasis |
| B | 0008198 | molecular_function | ferrous iron binding |
| B | 0008199 | molecular_function | ferric iron binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004322 | molecular_function | ferroxidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006826 | biological_process | iron ion transport |
| C | 0006879 | biological_process | intracellular iron ion homeostasis |
| C | 0008198 | molecular_function | ferrous iron binding |
| C | 0008199 | molecular_function | ferric iron binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004322 | molecular_function | ferroxidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006826 | biological_process | iron ion transport |
| D | 0006879 | biological_process | intracellular iron ion homeostasis |
| D | 0008198 | molecular_function | ferrous iron binding |
| D | 0008199 | molecular_function | ferric iron binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004322 | molecular_function | ferroxidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006826 | biological_process | iron ion transport |
| E | 0006879 | biological_process | intracellular iron ion homeostasis |
| E | 0008198 | molecular_function | ferrous iron binding |
| E | 0008199 | molecular_function | ferric iron binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004322 | molecular_function | ferroxidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006826 | biological_process | iron ion transport |
| F | 0006879 | biological_process | intracellular iron ion homeostasis |
| F | 0008198 | molecular_function | ferrous iron binding |
| F | 0008199 | molecular_function | ferric iron binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0042802 | molecular_function | identical protein binding |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE A1006 |
| Chain | Residue |
| A | GLU17 |
| A | GLU50 |
| A | HIS53 |
| A | ILE97 |
| A | GLN127 |
| A | GLU130 |
| A | FE1007 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A1007 |
| Chain | Residue |
| A | GLN127 |
| A | GLU130 |
| A | FE1006 |
| A | GLU50 |
| A | GLU94 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE B1006 |
| Chain | Residue |
| B | GLU17 |
| B | GLU50 |
| B | HIS53 |
| B | ILE97 |
| B | GLN127 |
| B | GLU130 |
| B | FE1007 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B1007 |
| Chain | Residue |
| B | GLU50 |
| B | GLU94 |
| B | GLN127 |
| B | GLU130 |
| B | FE1006 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE C1006 |
| Chain | Residue |
| C | GLU17 |
| C | GLU50 |
| C | HIS53 |
| C | GLN127 |
| C | GLU130 |
| C | FE1007 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE C1007 |
| Chain | Residue |
| C | GLU50 |
| C | GLU94 |
| C | GLN127 |
| C | GLU130 |
| C | FE1006 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE D1006 |
| Chain | Residue |
| D | GLU17 |
| D | GLU50 |
| D | HIS53 |
| D | GLN127 |
| D | GLU130 |
| D | FE1007 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE D1007 |
| Chain | Residue |
| D | GLU50 |
| D | GLU94 |
| D | GLN127 |
| D | GLU130 |
| D | FE1006 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE E1006 |
| Chain | Residue |
| E | GLU17 |
| E | GLU50 |
| E | HIS53 |
| E | GLN127 |
| E | GLU130 |
| E | FE1007 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE E1007 |
| Chain | Residue |
| E | GLU50 |
| E | GLU94 |
| E | GLN127 |
| E | GLU130 |
| E | FE1006 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE F1006 |
| Chain | Residue |
| F | GLU17 |
| F | GLU50 |
| F | HIS53 |
| F | GLN127 |
| F | GLU130 |
| F | FE1007 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE F1007 |
| Chain | Residue |
| F | GLU50 |
| F | GLU94 |
| F | GLN127 |
| F | GLU130 |
| F | FE1006 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL F1009 |
| Chain | Residue |
| A | MET18 |
| A | SER21 |
| A | ASN22 |
| A | TYR51 |
| F | MET18 |
| F | SER21 |
| F | ASN22 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL E1009 |
| Chain | Residue |
| B | MET18 |
| B | ASN22 |
| B | TYR51 |
| E | MET18 |
| E | SER21 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL D1008 |
| Chain | Residue |
| C | MET18 |
| C | SER21 |
| C | ASN22 |
| C | TYR51 |
| D | MET18 |
| D | SER21 |
| D | ASN22 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IPA A1009 |
| Chain | Residue |
| A | ASP106 |
| A | LYS110 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA D1009 |
| Chain | Residue |
| D | ASP106 |
| D | LYS110 |
| D | HOH1089 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IPA C1008 |
| Chain | Residue |
| C | ASP106 |
| F | HOH1128 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA A1010 |
| Chain | Residue |
| A | HOH1143 |
| F | ASP106 |
| F | ILE109 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IPA E1010 |
| Chain | Residue |
| E | ASP106 |
| E | LYS110 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IPA D1010 |
| Chain | Residue |
| B | ASP106 |
| B | LYS110 |
| D | HOH1136 |
| site_id | CC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IPA A1011 |
| Chain | Residue |
| A | SER98 |
| A | ILE101 |
| A | ASN102 |
| A | VAL124 |
| A | HIS128 |
| A | HOH1096 |
| A | HOH1109 |
| C | ALA115 |
| site_id | CC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IPA B1008 |
| Chain | Residue |
| B | SER98 |
| B | ILE101 |
| B | ASN102 |
| B | VAL124 |
| B | HIS128 |
| B | HOH1123 |
| D | ALA115 |
| D | HOH1141 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IPA C1009 |
| Chain | Residue |
| C | SER98 |
| C | ILE101 |
| C | ASN102 |
| C | VAL124 |
| C | HIS128 |
| C | HOH1138 |
| F | ALA115 |
| F | HOH1159 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE IPA D1011 |
| Chain | Residue |
| D | SER98 |
| D | ILE101 |
| D | ASN102 |
| D | HIS128 |
| D | HOH1115 |
| E | ALA115 |
| site_id | CC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IPA E1011 |
| Chain | Residue |
| B | ALA115 |
| B | HOH1106 |
| E | SER98 |
| E | ILE101 |
| E | ASN102 |
| E | VAL124 |
| E | HIS128 |
| E | HOH1107 |
| site_id | CC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IPA F1010 |
| Chain | Residue |
| A | ALA115 |
| A | HOH1140 |
| F | SER98 |
| F | ILE101 |
| F | ASN102 |
| F | VAL124 |
| F | HIS128 |
| F | HOH1108 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 864 |
| Details | Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
