Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3BVF

Structural basis for the iron uptake mechanism of Helicobacter pylori ferritin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding
B	0004322	molecular_function	ferroxidase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0016491	molecular_function	oxidoreductase activity
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0004322	molecular_function	ferroxidase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0016491	molecular_function	oxidoreductase activity
C	0042802	molecular_function	identical protein binding
C	0046872	molecular_function	metal ion binding
D	0004322	molecular_function	ferroxidase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0016491	molecular_function	oxidoreductase activity
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding
E	0004322	molecular_function	ferroxidase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0016491	molecular_function	oxidoreductase activity
E	0042802	molecular_function	identical protein binding
E	0046872	molecular_function	metal ion binding
F	0004322	molecular_function	ferroxidase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0016491	molecular_function	oxidoreductase activity
F	0042802	molecular_function	identical protein binding
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A1006

Chain	Residue
A	GLU17
A	GLU50
A	HIS53
A	ILE97
A	GLN127
A	GLU130
A	FE1007

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A1007

Chain	Residue
A	GLN127
A	GLU130
A	FE1006
A	GLU50
A	GLU94

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE B1006

Chain	Residue
B	GLU17
B	GLU50
B	HIS53
B	ILE97
B	GLN127
B	GLU130
B	FE1007

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE B1007

Chain	Residue
B	GLU50
B	GLU94
B	GLN127
B	GLU130
B	FE1006

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE C1006

Chain	Residue
C	GLU17
C	GLU50
C	HIS53
C	GLN127
C	GLU130
C	FE1007

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE C1007

Chain	Residue
C	GLU50
C	GLU94
C	GLN127
C	GLU130
C	FE1006

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE D1006

Chain	Residue
D	GLU17
D	GLU50
D	HIS53
D	GLN127
D	GLU130
D	FE1007

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE D1007

Chain	Residue
D	GLU50
D	GLU94
D	GLN127
D	GLU130
D	FE1006

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE E1006

Chain	Residue
E	GLU17
E	GLU50
E	HIS53
E	GLN127
E	GLU130
E	FE1007

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE E1007

Chain	Residue
E	GLU50
E	GLU94
E	GLN127
E	GLU130
E	FE1006

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE F1006

Chain	Residue
F	GLU17
F	GLU50
F	HIS53
F	GLN127
F	GLU130
F	FE1007

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE F1007

Chain	Residue
F	GLU50
F	GLU94
F	GLN127
F	GLU130
F	FE1006

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL F1009

Chain	Residue
A	MET18
A	SER21
A	ASN22
A	TYR51
F	MET18
F	SER21
F	ASN22

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL E1009

Chain	Residue
B	MET18
B	ASN22
B	TYR51
E	MET18
E	SER21

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D1008

Chain	Residue
C	MET18
C	SER21
C	ASN22
C	TYR51
D	MET18
D	SER21
D	ASN22

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA A1009

Chain	Residue
A	ASP106
A	LYS110

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA D1009

Chain	Residue
D	ASP106
D	LYS110
D	HOH1089

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA C1008

Chain	Residue
C	ASP106
F	HOH1128

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA A1010

Chain	Residue
A	HOH1143
F	ASP106
F	ILE109

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA E1010

Chain	Residue
E	ASP106
E	LYS110

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA D1010

Chain	Residue
B	ASP106
B	LYS110
D	HOH1136

site_id	CC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IPA A1011

Chain	Residue
A	SER98
A	ILE101
A	ASN102
A	VAL124
A	HIS128
A	HOH1096
A	HOH1109
C	ALA115

site_id	CC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IPA B1008

Chain	Residue
B	SER98
B	ILE101
B	ASN102
B	VAL124
B	HIS128
B	HOH1123
D	ALA115
D	HOH1141

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IPA C1009

Chain	Residue
C	SER98
C	ILE101
C	ASN102
C	VAL124
C	HIS128
C	HOH1138
F	ALA115
F	HOH1159

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IPA D1011

Chain	Residue
D	SER98
D	ILE101
D	ASN102
D	HIS128
D	HOH1115
E	ALA115

site_id	CC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IPA E1011

Chain	Residue
B	ALA115
B	HOH1106
E	SER98
E	ILE101
E	ASN102
E	VAL124
E	HIS128
E	HOH1107

site_id	CC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE IPA F1010

Chain	Residue
A	ALA115
A	HOH1140
F	SER98
F	ILE101
F	ASN102
F	VAL124
F	HIS128
F	HOH1108

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00085

Chain	Residue	Details
A	GLU17
B	GLN127
C	GLU17
C	GLU50
C	HIS53
C	GLU94
C	GLN127
D	GLU17
D	GLU50
D	HIS53
D	GLU94
A	GLU50
D	GLN127
E	GLU17
E	GLU50
E	HIS53
E	GLU94
E	GLN127
F	GLU17
F	GLU50
F	HIS53
F	GLU94
A	HIS53
F	GLN127
A	GLU94
A	GLN127
B	GLU17
B	GLU50
B	HIS53
B	GLU94

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)