3BT9
crystal structure of QacR(E57Q) bound to Dequalinium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006351 | biological_process | DNA-templated transcription |
| E | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 599 |
| Chain | Residue |
| A | ASN2 |
| A | ASP5 |
| A | LYS6 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 299 |
| Chain | Residue |
| A | LYS4 |
| A | TYR41 |
| A | HIS42 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 899 |
| Chain | Residue |
| D | LYS46 |
| D | THR23 |
| D | THR24 |
| D | THR25 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 900 |
| Chain | Residue |
| E | LYS36 |
| E | TYR40 |
| E | THR45 |
| E | LYS46 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 269 |
| Chain | Residue |
| B | LYS66 |
| D | ASN38 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 270 |
| Chain | Residue |
| D | LYS17 |
| D | GLU27 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 249 |
| Chain | Residue |
| E | TYR20 |
| E | THR45 |
| E | LYS46 |
| E | GLU47 |
| E | TYR106 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 699 |
| Chain | Residue |
| A | SER35 |
| A | LYS36 |
| E | LYS60 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 999 |
| Chain | Residue |
| D | TYR20 |
| D | LYS46 |
| D | GLU105 |
| D | TYR106 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 399 |
| Chain | Residue |
| E | LYS12 |
| E | ILE53 |
| E | ILE56 |
| E | GLN57 |
| E | LYS60 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 799 |
| Chain | Residue |
| A | TYR40 |
| E | ASN2 |
| E | ASP5 |
| E | LYS6 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 800 |
| Chain | Residue |
| A | THR23 |
| A | THR24 |
| A | THR25 |
| A | LYS46 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 499 |
| Chain | Residue |
| B | LYS67 |
| D | LYS60 |
| D | TYR91 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 801 |
| Chain | Residue |
| A | HIS128 |
| A | LYS132 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 279 |
| Chain | Residue |
| A | ASN2 |
| A | LEU3 |
| A | LYS4 |
| A | ASN38 |
| A | HIS42 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 280 |
| Chain | Residue |
| B | LYS73 |
| D | HIS164 |
| D | GLU165 |
| E | TYR107 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 E 239 |
| Chain | Residue |
| E | HIS128 |
| E | LYS132 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 602 |
| Chain | Residue |
| A | TYR80 |
| A | GLN180 |
| A | ASN184 |
| E | ILE70 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 810 |
| Chain | Residue |
| A | THR24 |
| A | GLY26 |
| A | GLU27 |
| site_id | CC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE DEQ A 201 |
| Chain | Residue |
| A | GLN57 |
| A | GLU58 |
| A | TRP61 |
| A | THR89 |
| A | TYR93 |
| A | TYR103 |
| A | TYR107 |
| A | GLU120 |
| B | ASN97 |
| B | THR161 |
| B | PHE162 |
Functional Information from PROSITE/UniProt
| site_id | PS01081 |
| Number of Residues | 31 |
| Details | HTH_TETR_1 TetR-type HTH domain signature. GYnatTTgeIvklseSSkGnLYyHFkTKen.L |
| Chain | Residue | Details |
| B | GLY19-LEU49 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
