3BP1
Crystal structure of putative 7-cyano-7-deazaguanine reductase QueF from Vibrio cholerae O1 biovar eltor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003674 | molecular_function | molecular_function |
| A | 0005575 | cellular_component | cellular_component |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008150 | biological_process | biological_process |
| A | 0008616 | biological_process | queuosine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0033739 | molecular_function | preQ1 synthase activity |
| A | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| B | 0003674 | molecular_function | molecular_function |
| B | 0005575 | cellular_component | cellular_component |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008150 | biological_process | biological_process |
| B | 0008616 | biological_process | queuosine biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0033739 | molecular_function | preQ1 synthase activity |
| B | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| C | 0003674 | molecular_function | molecular_function |
| C | 0005575 | cellular_component | cellular_component |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008150 | biological_process | biological_process |
| C | 0008616 | biological_process | queuosine biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0033739 | molecular_function | preQ1 synthase activity |
| C | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| D | 0003674 | molecular_function | molecular_function |
| D | 0005575 | cellular_component | cellular_component |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008150 | biological_process | biological_process |
| D | 0008616 | biological_process | queuosine biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0033739 | molecular_function | preQ1 synthase activity |
| D | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 288 |
| Chain | Residue |
| A | THR149 |
| A | HIS186 |
| A | HIS188 |
| A | HOH327 |
| A | HOH351 |
| A | HOH448 |
| C | PO4288 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 C 288 |
| Chain | Residue |
| B | THR143 |
| C | HIS210 |
| C | GLN251 |
| C | SER252 |
| C | HIS274 |
| A | PO4288 |
| A | HOH351 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 D 288 |
| Chain | Residue |
| B | PO4288 |
| D | THR149 |
| D | CYS154 |
| D | HIS186 |
| D | HIS188 |
| D | HOH353 |
| D | HOH358 |
| D | HOH461 |
| D | HOH483 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B 288 |
| Chain | Residue |
| B | HIS210 |
| B | GLN251 |
| B | SER252 |
| B | HIS274 |
| C | THR143 |
| D | THR149 |
| D | PO4288 |
| D | HOH353 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 289 |
| Chain | Residue |
| C | THR149 |
| C | HIS186 |
| C | HIS188 |
| C | HOH341 |
| C | HOH380 |
| C | HOH388 |
| C | HOH546 |
| C | HOH564 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 289 |
| Chain | Residue |
| B | THR149 |
| B | HIS186 |
| B | HIS188 |
| B | HOH350 |
| B | HOH380 |
| B | HOH389 |
| B | HOH488 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 289 |
| Chain | Residue |
| A | THR63 |
| A | TYR65 |
| A | ARG258 |
| A | ASP266 |
| A | ARG283 |
| A | GLN287 |
| A | HOH338 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG D 289 |
| Chain | Residue |
| D | THR63 |
| D | TYR65 |
| D | ARG258 |
| D | ASP266 |
| D | ARG283 |
| D | GLN287 |
| D | HOH344 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GUN B 290 |
| Chain | Residue |
| B | TRP62 |
| B | LEU92 |
| B | ILE93 |
| B | GLU94 |
| B | SER95 |
| B | PHE232 |
| B | HIS233 |
| B | GLU234 |
| B | ILE267 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GUN C 290 |
| Chain | Residue |
| C | TRP62 |
| C | LEU92 |
| C | ILE93 |
| C | GLU94 |
| C | SER95 |
| C | PHE232 |
| C | HIS233 |
| C | GLU234 |
| C | ILE267 |
| C | HOH530 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GUN A 290 |
| Chain | Residue |
| A | TRP62 |
| A | ILE93 |
| A | GLU94 |
| A | SER95 |
| A | PHE232 |
| A | HIS233 |
| A | GLU234 |
| A | ILE267 |
| A | HOH469 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GUN D 290 |
| Chain | Residue |
| D | TRP62 |
| D | ILE93 |
| D | GLU94 |
| D | SER95 |
| D | PHE232 |
| D | HIS233 |
| D | GLU234 |
| D | ILE267 |
| D | HOH487 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE POP B 291 |
| Chain | Residue |
| B | LYS99 |
| B | ARG261 |
| B | ARG262 |
| B | GLY263 |
| B | HOH299 |
| B | HOH305 |
| B | HOH585 |
| A | ARG262 |
| A | GLY263 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POP C 291 |
| Chain | Residue |
| C | LYS99 |
| C | GLN199 |
| C | ARG261 |
| C | ARG262 |
| C | GLY263 |
| C | HOH297 |
| C | HOH300 |
| C | HOH583 |
| D | ARG262 |
| D | GLY263 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Thioimide intermediate => ECO:0000255|HAMAP-Rule:MF_00817, ECO:0000269|Ref.3 |
| Chain | Residue | Details |
| A | CYS194 | |
| B | CYS194 | |
| C | CYS194 | |
| D | CYS194 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00817 |
| Chain | Residue | Details |
| A | ASP201 | |
| B | ASP201 | |
| C | ASP201 | |
| D | ASP201 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ILE93 | |
| B | SER95 | |
| B | HIS233 | |
| B | ARG262 | |
| C | ILE93 | |
| C | SER95 | |
| C | HIS233 | |
| C | ARG262 | |
| D | ILE93 | |
| D | SER95 | |
| D | HIS233 | |
| D | ARG262 | |
| A | ILE93 | |
| A | SER95 | |
| A | HIS233 | |
| A | ARG262 |
