3BH3
Crystal structure of acetoacetate decarboxylase from Chromobacterium violaceum in complex with acetyl acetone Schiff base intermediate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0047602 | molecular_function | acetoacetate decarboxylase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0047602 | molecular_function | acetoacetate decarboxylase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0047602 | molecular_function | acetoacetate decarboxylase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016831 | molecular_function | carboxy-lyase activity |
| D | 0047602 | molecular_function | acetoacetate decarboxylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PNH A 247 |
| Chain | Residue |
| A | ARG30 |
| A | TYR75 |
| A | LYS116 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PNH B 247 |
| Chain | Residue |
| B | ARG30 |
| B | TYR75 |
| B | PRO104 |
| B | PHE114 |
| B | LYS116 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PNH C 247 |
| Chain | Residue |
| C | PRO104 |
| C | LYS116 |
| C | ARG30 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PNH D 247 |
| Chain | Residue |
| D | ARG30 |
| D | MET97 |
| D | PHE114 |
| D | LYS116 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Schiff-base intermediate with acetoacetate","evidences":[{"source":"HAMAP-Rule","id":"MF_00597","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19458715","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"PubMed","id":"19458715","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
