3BEX
Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004594 | molecular_function | pantothenate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0043169 | molecular_function | cation binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004594 | molecular_function | pantothenate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0015937 | biological_process | coenzyme A biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0043169 | molecular_function | cation binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004594 | molecular_function | pantothenate kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0015937 | biological_process | coenzyme A biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0043169 | molecular_function | cation binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004594 | molecular_function | pantothenate kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0015937 | biological_process | coenzyme A biosynthetic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0043169 | molecular_function | cation binding |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0004594 | molecular_function | pantothenate kinase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0015937 | biological_process | coenzyme A biosynthetic process |
| E | 0016301 | molecular_function | kinase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0043169 | molecular_function | cation binding |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0004594 | molecular_function | pantothenate kinase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0015937 | biological_process | coenzyme A biosynthetic process |
| F | 0016301 | molecular_function | kinase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0043169 | molecular_function | cation binding |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 A 247 |
| Chain | Residue |
| A | GLY8 |
| A | HOH324 |
| A | HOH540 |
| A | ASN9 |
| A | THR10 |
| A | HIS11 |
| A | THR128 |
| A | HOH260 |
| A | HOH276 |
| A | HOH307 |
| A | HOH314 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 B 247 |
| Chain | Residue |
| B | GLY8 |
| B | ASN9 |
| B | THR10 |
| B | HIS11 |
| B | THR128 |
| B | HOH257 |
| B | HOH269 |
| B | HOH278 |
| B | HOH297 |
| B | HOH308 |
| B | HOH497 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 C 247 |
| Chain | Residue |
| C | GLY8 |
| C | ASN9 |
| C | THR10 |
| C | HIS11 |
| C | THR128 |
| C | HOH261 |
| C | HOH265 |
| C | HOH286 |
| C | HOH288 |
| C | HOH346 |
| C | HOH360 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PO4 D 247 |
| Chain | Residue |
| D | GLY8 |
| D | ASN9 |
| D | THR10 |
| D | HIS11 |
| D | THR128 |
| D | HOH263 |
| D | HOH291 |
| D | HOH312 |
| D | HOH319 |
| D | HOH341 |
| D | HOH393 |
| D | HOH549 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 E 247 |
| Chain | Residue |
| E | GLY8 |
| E | ASN9 |
| E | THR10 |
| E | HIS11 |
| E | THR128 |
| E | HOH264 |
| E | HOH292 |
| E | HOH293 |
| E | HOH295 |
| E | HOH322 |
| E | HOH434 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 F 247 |
| Chain | Residue |
| F | GLY8 |
| F | ASN9 |
| F | THR10 |
| F | HIS11 |
| F | THR128 |
| F | HOH265 |
| F | HOH274 |
| F | HOH288 |
| F | HOH293 |
| F | HOH325 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PAU A 248 |
| Chain | Residue |
| A | GLU101 |
| A | GLY103 |
| A | ASP105 |
| A | ARG106 |
| A | THR131 |
| A | HOH250 |
| A | HOH260 |
| A | HOH307 |
| A | HOH340 |
| B | LYS162 |
| B | LEU163 |
| B | THR179 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PAU B 248 |
| Chain | Residue |
| A | LYS162 |
| A | LEU163 |
| A | THR179 |
| B | GLU101 |
| B | GLY103 |
| B | ASP105 |
| B | ARG106 |
| B | HOH255 |
| B | HOH308 |
| B | HOH348 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PAU C 248 |
| Chain | Residue |
| C | GLU101 |
| C | GLY103 |
| C | ASP105 |
| C | ARG106 |
| C | HOH249 |
| C | HOH355 |
| C | HOH360 |
| D | LYS162 |
| D | THR179 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PAU D 248 |
| Chain | Residue |
| C | THR179 |
| D | GLU101 |
| D | GLY103 |
| D | ASP105 |
| D | ARG106 |
| D | HOH251 |
| D | HOH263 |
| D | HOH319 |
| D | HOH344 |
| C | LYS162 |
| C | LEU163 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PAU E 248 |
| Chain | Residue |
| E | GLU101 |
| E | GLY103 |
| E | ASP105 |
| E | ARG106 |
| E | THR131 |
| E | HOH256 |
| E | HOH320 |
| E | HOH322 |
| F | LYS162 |
| F | LEU163 |
| F | THR179 |
| site_id | BC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PAU F 248 |
| Chain | Residue |
| E | LYS162 |
| E | LEU163 |
| E | THR179 |
| F | GLU101 |
| F | GLY103 |
| F | ASP105 |
| F | ARG106 |
| F | HOH249 |
| F | HOH265 |
| F | HOH325 |
| F | HOH332 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
